Crocetin: a systematic review

ZL Guo, MX Li, XL Li, P Wang, WG Wang… - Frontiers in …, 2022 - frontiersin.org
Crocetin is an aglycone of crocin naturally occurring in saffron and produced in biological
systems by hydrolysis of crocin as a bioactive metabolite. It is known to exist in several …

[HTML][HTML] Recent Advances on the Anticancer Properties of Saffron (Crocus sativus L.) and Its Major Constituents

A Lambrianidou, F Koutsougianni, I Papapostolou… - Molecules, 2020 - mdpi.com
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in
2018 and a sustained rise in its incidence in both develo** and developed countries …

Crocins: A comprehensive review of structural characteristics, pharmacokinetics and therapeutic effects

Y Song, Y Wang, Y Zheng, T Liu, C Zhang - Fitoterapia, 2021 - Elsevier
Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Molecular and functional characterization of protease from psychrotrophic Bacillus sp. HM49 in North-western Himalaya

H Mushtaq, SA Ganai, A Jehangir, BA Ganai, R Dar - Plos one, 2023 - journals.plos.org
In this work, a psychrotrophic bacteria producing cold-active protease, was obtained from
Dachigam National Park, an ecologically significant habitat in Western Himalayas owing to …

[HTML][HTML] Deciphering genetic diversity analysis of saffron (Crocus sativus L.) using RAPD and ISSR markers

MA Mir, S Mansoor, M Sugapriya, MN Alyemeni… - Saudi Journal of …, 2021 - Elsevier
The existence of genetic diversity in Crocus sativus has globally remained a mystery till date.
The study investigated PCR based DNA amplification profile of saffron using ISSR and …

Biosynthesis of biomolecules from saffron as an industrial crop and their regulation, with emphasis on the chemistry, extraction methods, identification techniques, and …

V Gupta, G Jamwal, GK Rai, SK Gupta… - Biocatalysis and …, 2024 - Elsevier
The dried stigmas of Crocus sativus, known as “Red Gold,” are highly prized for their
nutritional and medicinal qualities. These qualities are due to the presence of …

Why cancer incidence in the Arab counties is much lower than other parts of the world?

MA Arafa, KH Farhat - Journal of the Egyptian National Cancer Institute, 2022 - Springer
Despite the relatively increased cancer incidence in the last few years in the Arab countries,
it is still far from the figures reported from Western countries. Several mechanisms have …

Glycerol Extraction of Bioactive Compounds from Thanaka (Hesperethusa crenulata) Bark through LCMS Profiling and Their Antioxidant Properties

MW Lim, Y Quan Tang, MK Aroua, LT Gew - ACS omega, 2024 - ACS Publications
Organic solvents are hazardous to human and environmental health. The emergence of
interest in finding greener solvents to replace organic solvents has sparked a series of …

Insights on the role of polyphenols in combating cancer drug resistance

M Farhan - Biomedicines, 2023 - mdpi.com
Chemotherapy resistance is still a serious problem in the treatment of most cancers. Many
cellular and molecular mechanisms contribute to both inherent and acquired drug …

Development and evaluation of crocetin-functionalized pegylated magnetite nanoparticles for hepatocellular carcinoma

S Ibrahim, B Baig, S Hisaindee, H Darwish… - Molecules, 2023 - mdpi.com
Liver cancer remains among the leading causes of cancer-related deaths worldwide. This is
due to many reasons, including limitations of available drugs, late diagnosis due to the …