High endothelial venules (HEVs) are specialized blood vessels mediating lymphocyte
trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high …

The effector phase of an immune response involves the secretion of protein mediators by
antigen-stimulated T lymphocytes, which serve to recruit and activate the various responsive …

The mucosal vascular addressin, MAdCAM-1, is an immunoglobulin superfamily adhesion
molecule for lymphocytes that is expressed by mucosal venules and helps direct lymphocyte …

We have cloned a previously undescribed adhesion molecule, VCAM-1, which is induced by
cytokines on human endothelial cells and binds lymphocytes. Using a novel method …

High endothelial venules (HEVs? are specialized postcapillary venules found in lymphoid
tissues that support high levels of lymphocyte extravasation from the blood. Here, Jean …

The tissue localization or" homing" of circulating lymphocytes is directed in part by
specialized vessels that define sites of lymphocyte exit from the blood. In peripheral lymph …

Publisher Summary This chapter discusses the lymphocyte trafficking and regional
immunity. The chapter discusses the present understanding of tissue-selective lymphocyte …

An endothelial cell surface molecule that is selectively expressed in mucosal organs is
required for lymphocyte homing to mucosal lymphoid tissues. This' vascular …

In a study of 151 normal, healthy individuals of both sexes varying in age from 1-70 yr, it was
found that the relative incidence of agalactosyl (with both outer arms terminating in N …

Lymphocyte interactions with high endothelial venules (HEV) during extravasation into
lymphoid tissues involve an 85-95 kd class of lymphocyte surface glycoprotein (s) …