Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
[HTML][HTML] Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
D Ha, N Yang, V Nadithe - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Exosomes are small intracellular membrane-based vesicles with different compositions that
are involved in several biological and pathological processes. The exploitation of exosomes …
are involved in several biological and pathological processes. The exploitation of exosomes …
Phosphoinositides: tiny lipids with giant impact on cell regulation
T Balla - Physiological reviews, 2013 - journals.physiology.org
Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …
control almost all aspects of a cell's life and death. These lipids gained tremendous research …
Sorting mechanisms for MicroRNAs into extracellular vesicles and their associated diseases
M Groot, H Lee - Cells, 2020 - mdpi.com
Extracellular vesicles (EV) are secretory membranous elements used by cells to transport
proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known …
proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known …
Exosomes: endosomal-derived vesicles ship** extracellular messages
B Février, G Raposo - Current opinion in cell biology, 2004 - Elsevier
Exosomes are membrane vesicles released into the extracellular environment upon exocytic
fusion of multivesicular endosomes with the cell surface. They have a particular composition …
fusion of multivesicular endosomes with the cell surface. They have a particular composition …
Body fluid derived exosomes as a novel template for clinical diagnostics
S Keller, J Ridinger, AK Rupp, JWG Janssen… - Journal of translational …, 2011 - Springer
Background Exosomes are small membrane vesicles with a size of 40-100 nm that are
released by different cell types from a late endosomal cellular compartment. They can be …
released by different cell types from a late endosomal cellular compartment. They can be …
Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials
Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …
require a thorough understanding of how they interact with cells, tissues, and organs. There …
Exosomes are released by cultured cortical neurones
J Fauré, G Lachenal, M Court, J Hirrlinger… - Molecular and Cellular …, 2006 - Elsevier
Accumulating evidence shows that several cell types have the capacity to secrete
membrane proteins by incorporating them into exosomes, which are small lipid vesicles …
membrane proteins by incorporating them into exosomes, which are small lipid vesicles …
Biogenesis and function of multivesicular bodies
RC Piper, DJ Katzmann - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
The two major cellular sites for membrane protein degradation are the proteasome and the
lysosome. Ubiquitin attachment is a sorting signal for both degradation routes. For lysosomal …
lysosome. Ubiquitin attachment is a sorting signal for both degradation routes. For lysosomal …
Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems
T Pawson - Cell, 2004 - cell.com
Over the last two decades, a new and unifying concept of cellular organization has emerged
in which modular protein-protein interactions provide an underlying framework through …
in which modular protein-protein interactions provide an underlying framework through …