Thrombospondin-1 is a secreted matricellular glycoprotein that modulates cell behavior by
interacting with components of the extracellular matrix and with several cell surface …

Abstract The classic Th1/Th2 dogma has been significantly reshaped since the subsequent
introduction of several new T helper cell subsets, among which the most intensively …

Despite constant exposure to various environmental stimuli, the ocular surface remains
intact and uninflamed while maintaining the transparency of the cornea and its visual …

Diabetes mellitus (DM) is one of the most prevalent diseases globally, and its prevalence is
rapidly increasing. Most patients with a long-term history of DM present with some degree of …

Abstract Thrombospondin 1 (TSP-1) is an extracellular matrix protein that interacts with a
wide array of ligands including cell receptors, growth factors, cytokines and proteases to …

The purpose of this study was to determine the pathogenic changes that occur in
myoepithelial cells (MECs) from lacrimal glands of a mouse model of Sjögren syndrome …

Neuropeptides are known as important mediators between the nervous and immune
systems. Recently, the role of the corneal nerve in the pathogenesis of various ocular …

The cornea is richly innervated with sensory nerves that function to detect and clear harmful
debris from the surface of the eye, promote growth and survival of the corneal epithelium …

Sjögren's syndrome (SS) is a systemic rheumatic disease that predominantly affects salivary
and lacrimal glands resulting in oral and ocular dryness, respectively, referred to as sicca …

Backgroud The frequencies of morbidity and impairment associated with spontaneous
intracerebral haemorrhage (ICH) are comparatively high. Blood-brain barrier (BBB) integrity …