A brain organoid is a self-organizing three-dimensional tissue derived from human
embryonic stem cells or pluripotent stem cells and is able to simulate the architecture and …

The mesenchymal subtype of glioblastoma is thought to be determined by both cancer cell-
intrinsic alterations and extrinsic cellular interactions, but remains poorly understood. Here …

Rodent brain tumor models have been useful for develo** effective therapies for
glioblastomas (GBMs). In this review, we first discuss the 3 most commonly used rat brain …

The resolution and dimensionality with which biologists can characterize cell types have
expanded dramatically in recent years, and intersectional consideration of such features (eg …

Primary brain tumors are a heterogeneous group of malignancies that originate in cells of
the central nervous system. A variety of models tractable for preclinical studies have been …

Glioblastoma is the most common malignant primary central nervous system tumor and one
of the most debilitating cancers. The prognosis of patients with glioblastoma remains poor …

Simple Summary Glioblastoma multiforme (GBM) is the most common type of malignant
brain tumor. GBM patients face a dire future, as they rarely survive longer than 15 months …

Rotator cuff supraspinatus tendon injuries are common with high rates of anatomic failure
after surgical repair. The purpose of the study was to define clinically relevant features of a …

Astrocytes provide trophic and metabolic support to neurons and modulate circuit formation
during development. In addition, astrocytes help maintain neuronal homeostasis through …

Simple Summary Glioblastoma multiforme (GBM) ranks as the most frequent form of primary
malignant brain tumor. The prognosis for individuals diagnosed with this disease typically …