Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

Cortical processing reflects the interplay of synaptic excitation and synaptic inhibition.
Rapidly accumulating evidence is highlighting the crucial role of inhibition in sha** …

The active electrical properties of dendrites shape neuronal input and output and are
fundamental to brain function. However, our knowledge of active dendrites has been almost …

Extended wakefulness is associated with reduced performance and the build-up of sleep
pressure. In the cortex, this manifests as changes in network activity. These changes show …

Synaptic inhibition plays a crucial role in regulating neuronal excitability, which is the
foundation of nervous system function. This inhibition is largely mediated by the …

GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the
main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and …

Spike timing–dependent plasticity (STDP) as a Hebbian synaptic learning rule has been
demonstrated in various neural circuits over a wide spectrum of species, from insects to …

Gamma frequency oscillations are thought to provide a temporal structure for information
processing in the brain. They contribute to cognitive functions, such as memory formation …

The proper functioning of the adult mammalian brain relies on the orchestrated regulation of
neural activity by a diverse population of GABA (γ-aminobutyric acid)-releasing neurons …

Develo** networks follow common rules to shift from silent cells to coactive networks that
operate via thousands of synapses. This review deals with some of these rules and in …