Neurobiological interactions between stress and the endocannabinoid system
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …
many neurobehavioral processes. A growing body of work indicates that the …
Involvement of the endocannabinoid system in drug addiction
Recent studies have shown that the endocannabinoid system is involved in the common
neurobiological mechanism underlying drug addiction. This system participates in the …
neurobiological mechanism underlying drug addiction. This system participates in the …
Endocannabinoid signaling and long-term synaptic plasticity
Endocannabinoids (eCBs) are key activity-dependent signals regulating synaptic
transmission throughout the central nervous system. Accordingly, eCBs are involved in …
transmission throughout the central nervous system. Accordingly, eCBs are involved in …
Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex
VA Bender, KJ Bender, DJ Brasier… - Journal of …, 2006 - Soc Neuroscience
Many cortical synapses exhibit spike timing-dependent plasticity (STDP) in which the
precise timing of presynaptic and postsynaptic spikes induces synaptic strengthening [long …
precise timing of presynaptic and postsynaptic spikes induces synaptic strengthening [long …
Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure
MN Hill, SA Kumar, SB Filipski, M Iverson… - Molecular …, 2013 - nature.com
Hyperactivation of the amygdala following chronic stress is believed to be one of the primary
mechanisms underlying the increased propensity for anxiety-like behaviors and pathological …
mechanisms underlying the increased propensity for anxiety-like behaviors and pathological …
Presynaptic long-term plasticity
Y Yang, N Calakos - Frontiers in synaptic neuroscience, 2013 - frontiersin.org
Long-term synaptic plasticity is a major cellular substrate for learning, memory, and
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …
Mechanisms of endocannabinoid control of synaptic plasticity
The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …
Synaptic plasticity and drug addiction
S Jones, A Bonci - Current opinion in pharmacology, 2005 - Elsevier
Recent studies have suggested that the development of addictive behaviours shares
common features with traditional learning models. Synaptic plasticity, a possible substrate …
common features with traditional learning models. Synaptic plasticity, a possible substrate …
Presynaptic spike timing-dependent long-term depression in the mouse hippocampus
Spike timing-dependent plasticity (STDP) is a Hebbian learning rule important for synaptic
refinement during development and for learning and memory in the adult. Given the …
refinement during development and for learning and memory in the adult. Given the …
Presynaptic modulation by endocannabinoids
DM Lovinger - Pharmacology of Neurotransmitter Release, 2008 - Springer
Modulation of neurotransmitter release by G-protein-coupled receptors (GPCRs) is a
prominent presynaptic mechanism for regulation of synaptic transmission. Activation of …
prominent presynaptic mechanism for regulation of synaptic transmission. Activation of …