SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes

CI Wu, PG Postema, E Arbelo, ER Behr, CR Bezzina… - Heart rhythm, 2020 - Elsevier
Ever since the first case was reported at the end of 2019, the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease 2019 …

Seizures and epilepsy: an overview for neuroscientists

CE Stafstrom, L Carmant - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epilepsy is one of the most common and disabling neurologic conditions, yet we have an
incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for …

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

SM Zuberi, E Wirrell, E Yozawitz, JM Wilmshurst… - …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

Incidence and phenotypes of childhood-onset genetic epilepsies: a prospective population-based national cohort

JD Symonds, SM Zuberi, K Stewart, A McLellan… - Brain, 2019 - academic.oup.com
Epilepsy is common in early childhood. In this age group it is associated with high rates of
therapy-resistance, and with cognitive, motor, and behavioural comorbidity. A large number …

The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications

A Brunklaus, T Brünger, T Feng, C Fons, A Lehikoinen… - Brain, 2022 - academic.oup.com
Brain voltage-gated sodium channel NaV1. 1 (SCN1A) loss-of-function variants cause the
severe epilepsy Dravet syndrome, as well as milder phenotypes associated with genetic …

[HTML][HTML] Epilepsy-associated genes

J Wang, ZJ Lin, L Liu, HQ Xu, YW Shi, YH Yi, N He… - Seizure, 2017 - Elsevier
Abstract Development in genetic technology has led to the identification of an increasing
number of genes associated with epilepsy. These discoveries will both provide the basis for …

Drosophila tools and assays for the study of human diseases

B Ugur, K Chen, HJ Bellen - Disease models & mechanisms, 2016 - journals.biologists.com
Many of the internal organ systems of Drosophila melanogaster are functionally analogous
to those in vertebrates, including humans. Although humans and flies differ greatly in terms …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

SCN1A‐related phenotypes: epilepsy and beyond

IE Scheffer, R Nabbout - Epilepsia, 2019 - Wiley Online Library
SCN1A, encoding the alpha 1 subunit of the sodium channel, is associated with several
epilepsy syndromes and a range of other diseases. SCN1A represents the archetypal …

Sodium channelopathies in neurodevelopmental disorders

MH Meisler, SF Hill, W Yu - Nature Reviews Neuroscience, 2021 - nature.com
The voltage-gated sodium channel α-subunit genes comprise a highly conserved gene
family. Mutations of three of these genes, SCN1A, SCN2A and SCN8A, are responsible for a …