Chemically modified water-soluble chitosan derivatives: Modification strategies, biological activities, and applications

WR Wan Yusof, NYF Awang… - Polymer-Plastics …, 2023 - Taylor & Francis
Chitosan, a biocompatible and nontoxic heteropolymer derived from chitin, offers various
applications. However, its limited solubility above pH 6.5 hinders its broader applications …

[HTML][HTML] Neurotoxic Effects of Linalool and β-Pinene on Tribolium castaneum Herbst

N Pajaro-Castro, K Caballero-Gallardo… - Molecules, 2017 - mdpi.com
Effective, ethical pest control requires the use of chemicals that are highly specific, safe, and
ecofriendly. Linalool and β-pinene occur naturally as major constituents of the essential oils …

Engineering of a chitin deacetylase to generate tailor-made chitosan polymers

M Bonin, AL Irion, A Jürß, S Pascual… - PLoS …, 2024 - journals.plos.org
Chitin deacetylases (CDAs) emerge as a valuable tool to produce chitosans with a
nonrandom distribution of N-acetylglucosamine (GlcNAc) and glucosamine (GlcN) units. We …

In silico and in vitro analysis of an Aspergillus niger chitin deacetylase to decipher its subsite sugar preferences

M Bonin, L Hameleers, L Hembach, T Roret… - Journal of Biological …, 2021 - jbc.org
Chitin deacetylases (CDAs) are found in many different organisms ranging from marine
bacteria to fungi and insects. These enzymes catalyze the removal of acetyl groups from …

Molecular modelling on SARS-CoV-2 papain-like protease: an integrated study with homology modelling, molecular docking, and molecular dynamics simulations

A Arwansyah, AR Arif, I Ramli, I Kurniawan… - SAR and QSAR in …, 2021 - Taylor & Francis
ABSTRACT SARS-CoV-2 PLpro was investigated as a therapeutic target for potent antiviral
drugs due to its essential role in not only viral replication but also in regulating the inborn …

Efficient degradation of 4-nitrophenol and colorimetric detection of Fe (III) by biogenic silver nanoparticles of Papiliotrema laurentii

J Majumder, T Bhunia, S Gorai, D De… - Materials Science and …, 2023 - Elsevier
In this study, novel biogenic silver nanoparticles have been developed involving a green
method by a yeast strain, Papiliotrema laurentii (Y24) cell resuspension exudate. Synthesis …

Purification, characterization, molecular modeling and docking study of fish waste protease

R Saranya, J Jayapriya - International Journal of Biological …, 2018 - Elsevier
In the present study, the alkaline protease has been extracted from the fish processing waste
using ammonium sulphate fractionation followed by ion-exchange chromatography on …

Proteogenomic approaches to understand gene mutations and protein structural alterations in colon cancer

S Sarkar - Physiologia, 2023 - mdpi.com
With colon cancer being one of the deadliest and most common cancers, understanding the
mechanisms behind colon cancer is crucial in improving therapies. One of the newest …

Experimental and computational approaches to improve binding affinity in chemical biology and drug discovery

A Nayarisseri - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
Drug discovery is one of the most complicated processes and establishment of a single drug
may require multidisciplinary attempts to design efficient and commercially viable drugs. The …

Isolation, characterisation, and genome sequencing of Rhodococcus equi: a novel strain producing chitin deacetylase

Q Ma, X Gao, X Bi, L Tu, M **a, Y Shen, M Wang - Scientific Reports, 2020 - nature.com
Chitin deacetylase (CDA) can hydrolyse the acetamido group of chitin polymers to produce
chitosans, which are used in various fields including the biomedical and pharmaceutical …