A systematic review of the valproic-acid-induced rodent model of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
Three decades of valproate: a current model for studying autism Spectrum disorder
D Zarate-Lopez, AL Torres-Chávez… - Current …, 2024 - benthamdirect.com
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
A standardized social preference protocol for measuring social deficits in mouse models of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
communication deficits and other behavioral abnormalities. The three-chamber social …
communication deficits and other behavioral abnormalities. The three-chamber social …
Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …
executive functioning and communication deficits with those described in several …
[HTML][HTML] Emerging mechanisms of valproic acid-induced neurotoxic events in autism and its implications for pharmacological treatment
A Taleb, W Lin, X Xu, G Zhang, QG Zhou… - Biomedicine & …, 2021 - Elsevier
Autism spectrum disorder (ASD) is a sort of mental disorder marked by deficits in cognitive
and communication abilities. To date no effective cure for this pernicious disease has been …
and communication abilities. To date no effective cure for this pernicious disease has been …
Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder
AM Tartaglione, S Schiavi, G Calamandrei, V Trezza - Neuropharmacology, 2019 - Elsevier
Impairments in social interaction and verbal and non verbal communication are among the
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
main features of Autism Spectrum Disorder (ASD). The causes of ASD are still unknown but …
Histamine, neuroinflammation and neurodevelopment: a review
E Carthy, T Ellender - Frontiers in neuroscience, 2021 - frontiersin.org
The biogenic amine, histamine, has been shown to critically modulate inflammatory
processes as well as the properties of neurons and synapses in the brain, and is also …
processes as well as the properties of neurons and synapses in the brain, and is also …
The impact of glutathione metabolism in autism spectrum disorder
This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …
Targeting microglia in neuroinflammation: H3 receptor antagonists as a novel therapeutic approach for Alzheimer's disease, Parkinson's disease, and autism spectrum …
Histamine performs dual roles as an immune regulator and a neurotransmitter in the
mammalian brain. The histaminergic system plays a vital role in the regulation of …
mammalian brain. The histaminergic system plays a vital role in the regulation of …
Discovery of a small molecule drug candidate for selective NKCC1 inhibition in brain disorders
Aberrant expression ratio of Cl− transporters, NKCC1 and KCC2, is implicated in several
brain conditions. NKCC1 inhibition by the FDA-approved diuretic drug, bumetanide, rescues …
brain conditions. NKCC1 inhibition by the FDA-approved diuretic drug, bumetanide, rescues …