Integrin crosstalk contributes to the complexity of signalling and unpredictable cancer cell fates

I Samaržija, A Dekanić, JD Humphries, M Paradžik… - Cancers, 2020 - mdpi.com
Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …

BP180/Collagen XVII: A molecular view

J Tuusa, N Kokkonen, K Tasanen - International journal of molecular …, 2021 - mdpi.com
BP180 is a type II collagenous transmembrane protein and is best known as the major
autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a …

The nexus of inflammation-induced epithelial-mesenchymal transition and lung cancer progression: a roadmap to pentacyclic triterpenoid-based therapies

KV Odarenko, MA Zenkova, AV Markov - International Journal of …, 2023 - mdpi.com
Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is
partly due to chronic inflammation that accompanies the disease and stimulates cancer …

The interactome of cancer-related lysyl oxidase and lysyl oxidase-like proteins

SD Vallet, C Berthollier, R Salza, L Muller… - Cancers, 2020 - mdpi.com
Simple Summary The members of the lysyl oxidase (LOX) family initiate covalent cross-
linking of the extracellular matrix and contribute to cancer progression. The aim of this study …

A review of acquired autoimmune blistering diseases in inherited epidermolysis bullosa: implications for the future of gene therapy

PM Patel, VA Jones, CT Behnam, G Di Zenzo… - Antibodies, 2021 - mdpi.com
Gene therapy serves as a promising therapy in the pipeline for treatment of epidermolysis
bullosa (EB). However, with great promise, the risk of autoimmunity must be considered …

[HTML][HTML] The Mclust Analysis of Tumor Budding Unveils the Role of the Collagen Family in Cervical Cancer Progression

OEM Lee, TM Le, GO Chong, JJ Cho, NJY Park - Life, 2024 - mdpi.com
In RNA-seq data analysis, condensing the gene count matrix size is pivotal for downstream
investigations, particularly pathway analysis. For this purpose, harnessing machine learning …

[HTML][HTML] White Light Diffraction Phase Microscopy in Imaging of Breast and Colon Tissues

A Smarandache, RA Pirvulescu, IR Andrei, A Dinache… - Diagnostics, 2024 - mdpi.com
This paper reports results obtained using white light diffraction phase microscopy (wDPM)
on captured images of breast and colon tissue samples, marking a contribution to the …

An analysis of the pathogenesis of Epidermolysis Bullosa and the future for curative treatments

R Magesh - 2023 - open.bu.edu
Epidermolysis Bullosa (EB) is a rare genetic disorder that causes extreme skin fragility and
blistering in patients, significantly impacting their quality of life. EB can be classified into …