Integrin crosstalk contributes to the complexity of signalling and unpredictable cancer cell fates
Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …
BP180/Collagen XVII: A molecular view
J Tuusa, N Kokkonen, K Tasanen - International journal of molecular …, 2021 - mdpi.com
BP180 is a type II collagenous transmembrane protein and is best known as the major
autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a …
autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a …
The nexus of inflammation-induced epithelial-mesenchymal transition and lung cancer progression: a roadmap to pentacyclic triterpenoid-based therapies
Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is
partly due to chronic inflammation that accompanies the disease and stimulates cancer …
partly due to chronic inflammation that accompanies the disease and stimulates cancer …
The interactome of cancer-related lysyl oxidase and lysyl oxidase-like proteins
SD Vallet, C Berthollier, R Salza, L Muller… - Cancers, 2020 - mdpi.com
Simple Summary The members of the lysyl oxidase (LOX) family initiate covalent cross-
linking of the extracellular matrix and contribute to cancer progression. The aim of this study …
linking of the extracellular matrix and contribute to cancer progression. The aim of this study …
A review of acquired autoimmune blistering diseases in inherited epidermolysis bullosa: implications for the future of gene therapy
Gene therapy serves as a promising therapy in the pipeline for treatment of epidermolysis
bullosa (EB). However, with great promise, the risk of autoimmunity must be considered …
bullosa (EB). However, with great promise, the risk of autoimmunity must be considered …
[HTML][HTML] The Mclust Analysis of Tumor Budding Unveils the Role of the Collagen Family in Cervical Cancer Progression
In RNA-seq data analysis, condensing the gene count matrix size is pivotal for downstream
investigations, particularly pathway analysis. For this purpose, harnessing machine learning …
investigations, particularly pathway analysis. For this purpose, harnessing machine learning …
[HTML][HTML] White Light Diffraction Phase Microscopy in Imaging of Breast and Colon Tissues
This paper reports results obtained using white light diffraction phase microscopy (wDPM)
on captured images of breast and colon tissue samples, marking a contribution to the …
on captured images of breast and colon tissue samples, marking a contribution to the …
An analysis of the pathogenesis of Epidermolysis Bullosa and the future for curative treatments
R Magesh - 2023 - open.bu.edu
Epidermolysis Bullosa (EB) is a rare genetic disorder that causes extreme skin fragility and
blistering in patients, significantly impacting their quality of life. EB can be classified into …
blistering in patients, significantly impacting their quality of life. EB can be classified into …