Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Importance β-Lactam antibiotics are among the safest and most effective antibiotics. Many
patients report allergies to these drugs that limit their use, resulting in the use of broad …

Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …

The intent of this document is to highlight practical recommendations in a concise format
designed to assist acute-care hospitals in implementing and prioritizing their surgical-site …

Penicillin Allergy Many more patients are labeled as penicillin-allergic than actually are
allergic. The label should be analyzed with skin testing and test exposure. Patients with true …

Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …

These guidelines for the treatment of persons who have or are at risk for sexually transmitted
infections (STIs) were updated by CDC after consultation with professionals knowledgeable …

The increasing incidence of antimicrobial resistance (AMR) presents a global crisis to
healthcare, with longstanding antimicrobial agents becoming less effective at treating and …

The belief that, for the individual patient, the benefit of prompt and continued use of
antimicrobials outweighs any potential harm is a significant barrier to improved stewardship …

Importance Cefazolin is the preoperative antibiotic of choice because it is safer and more
efficacious than second-line alternatives. Surgical patients labeled as having penicillin …