Reelin functions, mechanisms of action and signaling pathways during brain development and maturation

Y Jossin - Biomolecules, 2020 - mdpi.com
During embryonic development and adulthood, Reelin exerts several important functions in
the brain including the regulation of neuronal migration, dendritic growth and branching …

The involvement of Reelin in neurodevelopmental disorders

TD Folsom, SH Fatemi - Neuropharmacology, 2013 - Elsevier
Reelin is a glycoprotein that serves important roles both during development (regulation of
neuronal migration and brain lamination) and in adulthood (maintenance of synaptic …

Reelin and neuropsychiatric disorders

K Ishii, K Kubo, K Nakajima - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Proper neuronal migration and laminar formation during corticogenesis is essential for
normal brain function. Disruption of these developmental processes is thought to be …

[HTML][HTML] OCRL1 Deficiency Affects the Intracellular Traffic of ApoER2 and Impairs Reelin-Induced Responses

LM Fuentealba, H Pizarro, MP Marzolo - Biomolecules, 2024 - mdpi.com
Lowe Syndrome (LS) is a rare X-linked disorder characterized by renal dysfunction,
cataracts, and several central nervous system (CNS) anomalies. The mechanisms …

[HTML][HTML] Shared Molecular Signature in Alzheimer's Disease and Schizophrenia: A Systematic Review of the Reelin Signaling Pathway

AI Valderrama-Mantilla, C Martín-Cuevas… - Neuroscience & …, 2025 - Elsevier
The Reelin signaling pathway, particularly the RELN-APOER2-DAB1 complex, has emerged
as a key contributor to the neuropathology of Alzheimer's disease (AD) and Schizophrenia …

The role of reelin signaling in Alzheimer's disease

NN Yu, MS Tan, JT Yu, AM **
Alzheimer's disease (AD) was examined in a sample of 432 patients and 308 controls …