Frailty in rheumatic diseases

F Motta, A Sica, C Selmi - Frontiers in immunology, 2020 - frontiersin.org
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of
several systems, leading to increased vulnerability and adverse health outcomes. While …

Accumulating awareness on the clinical significance and relevance of frailty in cirrhosis: Time to dig deeper into mechanistic basis!

Y Deng, Y Hui, B Cui, W **e, C Sun - Liver International, 2023 - Wiley Online Library
Frailty corresponds to an emerging construct in the hepatology which is originally introduced
as a validated geriatric syndrome regarding increased vulnerability to pathophysiological …

Incidence and bedside predictors of the first episode of overt hepatic encephalopathy in patients with cirrhosis

EB Tapper, L Zhao, S Nikirk, J Baki… - Official journal of the …, 2020 - journals.lww.com
METHODS: We prospectively enrolled 294 subjects with Child AB (70% Child A) cirrhosis
and portal hypertension without previous HE from July 2016 to August 2018. The primary …

Falls are common, morbid, and predictable in patients with cirrhosis

EB Tapper, S Nikirk, ND Parikh, L Zhao - Journal of hepatology, 2021 - Elsevier
Background & Aims Falls are a devastating complication of cirrhosis. The risk of falls in
patients without hepatic encephalopathy (HE) is unclear. Further, bedside tools for …

Cognitive function, sarcopenia, and inflammation are strongly associated with frailty: a Framingham cohort study

M Mehta, J Louissaint, NS Parikh, MT Long… - The American journal of …, 2021 - Elsevier
Background Frailty is an important contributor to morbidity and mortality in chronic liver
disease. Understanding the contributors to frailty has the potential to identify individuals at …

Executive function is associated with balance and falls in older cancer survivors treated with chemotherapy: A cross-sectional study

BL McNeish, K Dittus, J Mossburg, N Krant… - Journal of geriatric …, 2023 - Elsevier
Introduction Balance decrements and increased fall risk in older cancer survivors have been
attributed to chemotherapy-induced peripheral neuropathy (CIPN). Cognition is also affected …

[HTML][HTML] Motor and cognitive performance in patients with liver cirrhosis with minimal hepatic encephalopathy

C San Martín-Valenzuela, A Borras-Barrachina… - Journal of clinical …, 2020 - mdpi.com
Minimal hepatic encephalopathy (MHE) is associated with mild cognitive impairment and
frailty. This study aims to identify cognitive and motor differences in cirrhotic patients with …

Risk factors for poorer health literacy in patients with liver cirrhosis

L Kaps, K Hildebrand, M Nagel, M Michel… - PLoS …, 2021 - journals.plos.org
Background Health literacy is a concept that refers to patients' ability to manage their
disease and the health system's ability to guarantee access to services. There is evidence …

[PDF][PDF] Cognitive impairment and physical frailty in patients with cirrhosis

K Berry, A Duarte‐Rojo, JD Grab… - Hepatology …, 2022 - Wiley Online Library
Physical frailty and impaired cognition are common in patients with cirrhosis. Physical frailty
can be assessed using performance‐based tests, but the extent to which impaired cognition …

[HTML][HTML] Liver frailty index for prediction of short-term rehospitalization in patients with liver cirrhosis

L Kaps, L Lukac, M Michel, WM Kremer, M Hilscher… - Diagnostics, 2022 - mdpi.com
Background: Stratifying patients with liver cirrhosis for risk of rehospitalization is challenging
with established scoring systems for chronic liver disease. Frailty captures the physical …