Epidemiological characteristics of human prion diseases
C Chen, XP Dong - Infectious diseases of poverty, 2016 - Springer
Human prion diseases are a group of transmissible, progressive, and invariably fatal
neurodegenerative disorders, which include Kuru, Creutzfeldt-Jakob disease (CJD) …
neurodegenerative disorders, which include Kuru, Creutzfeldt-Jakob disease (CJD) …
14-3-3 proteins as potential therapeutic targets
The 14-3-3 family of phosphoserine/phosphothreonine-binding proteins dynamically
regulates the activity of client proteins in various signaling pathways that control diverse …
regulates the activity of client proteins in various signaling pathways that control diverse …
YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias
Background YKL-40 (also known as Chitinase 3-like 1) is a glycoprotein produced by
inflammatory, cancer and stem cells. Its physiological role is not completely understood but …
inflammatory, cancer and stem cells. Its physiological role is not completely understood but …
Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological …
The differential diagnosis of Creutzfeldt-Jakob disease (CJD) from other, sometimes
treatable, neurological disorders is challenging, owing to the wide phenotypic heterogeneity …
treatable, neurological disorders is challenging, owing to the wide phenotypic heterogeneity …
Validation and utilization of amended diagnostic criteria in Creutzfeldt-Jakob disease surveillance
Objective To validate an amended protocol for clinical diagnosis of sporadic Creutzfeldt-
Jakob disease (sCJD) including real-time quaking-induced conversion (RT-QuIC) and to …
Jakob disease (sCJD) including real-time quaking-induced conversion (RT-QuIC) and to …
Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay
Introduction The definitive diagnosis of genetic prion diseases (gPrD) requires pathological
confirmation. To date, diagnosis has relied upon the finding of the biomarkers 14-3-3 protein …
confirmation. To date, diagnosis has relied upon the finding of the biomarkers 14-3-3 protein …
Tau and p-tau as CSF biomarkers in dementia: a meta-analysis
AC van Harten, MI Kester, PJ Visser… - Clinical chemistry and …, 2011 - degruyter.com
Background: To evaluate the value of total tau (tau) and phosphorylated tau (p-tau) in
cerebrospinal fluid (CSF) in the differential diagnosis of dementia, more specifically …
cerebrospinal fluid (CSF) in the differential diagnosis of dementia, more specifically …
Plasma and cerebrospinal fluid tau and neurofilament concentrations in rapidly progressive neurological syndromes: a neuropathology‐based cohort
GG Kovacs, U Andreasson, V Liman… - European Journal of …, 2017 - Wiley Online Library
Background and purpose Cerebrospinal fluid (CSF) tau and neurofilament light chain (NF‐
L) proteins have proved to be reliable biomarkers for neuronal damage; however, there is a …
L) proteins have proved to be reliable biomarkers for neuronal damage; however, there is a …
Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases
Genetic prion diseases are a rare and diverse group of fatal neurodegenerative disorders
caused by pathogenic sequence variations in the prion protein gene, PRNP. Data on CSF …
caused by pathogenic sequence variations in the prion protein gene, PRNP. Data on CSF …
Fatal familial insomnia and sporadic fatal insomnia
L Cracco, BS Appleby, P Gambetti - Handbook of clinical neurology, 2018 - Elsevier
Fatal familial insomnia (FFI) and sporadic fatal insomnia (sFI), or thalamic form of sporadic
Creutzfeldt–Jakob disease MM2 (sCJDMM2T), are prion diseases originally named and …
Creutzfeldt–Jakob disease MM2 (sCJDMM2T), are prion diseases originally named and …