[HTML][HTML] Brain edema formation and therapy after intracerebral hemorrhage

Y Wan, KG Holste, Y Hua, RF Keep, G ** - Neurobiology of disease, 2023 - Elsevier
Intracerebral hemorrhage (ICH) accounts for about 10% of all strokes in the United States of
America causing a high degree of disability and mortality. There is initial (primary) brain …

Perihematomal edema after intracerebral hemorrhage: an update on pathogenesis, risk factors, and therapeutic advances

Y Chen, S Chen, J Chang, J Wei, M Feng… - Frontiers in …, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

Current management of spontaneous intracerebral haemorrhage

CK Dastur, W Yu - Stroke and vascular neurology, 2017 - svn.bmj.com
Intracerebral haemorrhage (ICH) is the most devastating and disabling type of stroke.
Uncontrolled hypertension (HTN) is the most common cause of spontaneous ICH. Recent …

Computed tomography in acute intracerebral hemorrhage: neuroimaging predictors of hematoma expansion and outcome

A Hillal, T Ullberg, B Ramgren, J Wassélius - Insights into imaging, 2022 - Springer
Intracerebral hemorrhage (ICH) accounts for 10–20% of all strokes worldwide and is
associated with serious outcomes, including a 30-day mortality rate of up to 40 …

Perihematomal edema after spontaneous intracerebral hemorrhage

N Ironside, CJ Chen, D Ding, SA Mayer, ES Connolly Jr - Stroke, 2019 - ahajournals.org
Ironside et al Perihematomal Edema and ICH 1627 common pathway of the coagulation
cascade. 39 Thrombin can also induce PHE formation independent of fibrinogen, which …

Perihematomal edema and functional outcomes in intracerebral hemorrhage: influence of hematoma volume and location

SB Murthy, Y Moradiya, J Dawson, KR Lees… - Stroke, 2015 - ahajournals.org
Background and Purpose—Perihematomal edema (PHE) is associated with poor outcomes
after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a …

[HTML][HTML] Advances in therapeutic approaches for spontaneous intracerebral hemorrhage

MN Al-Kawaz, DF Hanley, W Ziai - Neurotherapeutics, 2020 - Elsevier
Spontaneous intracerebral hemorrhage (ICH) results in high rates of morbidity and mortality,
with intraventricular hemorrhage (IVH) being associated with even worse outcomes …

Molecular, pathological, clinical, and therapeutic aspects of perihematomal edema in different stages of intracerebral hemorrhage

C Jiang, H Guo, Z Zhang, Y Wang, S Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal
destruction involved in the brain damage process caused by ICH includes a primary injury …

miR-27a-3p protects against blood–brain barrier disruption and brain injury after intracerebral hemorrhage by targeting endothelial aquaporin-11

T **, F **, Y Zhu, J Wang, L Tang, Y Wang… - Journal of Biological …, 2018 - jbc.org
Previous studies have reported that miR-27a-3p is down-regulated in the serum of patients
with intracerebral hemorrhage (ICH), but the implication of miR-27a-3p down-regulation in …

Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage

S Reyes-Esteves, J Nong, PM Glassman… - Journal of Controlled …, 2023 - Elsevier
Intracerebral hemorrhage (ICH) is one of the most common causes of fatal stroke, yet has no
specific drug therapies. Many attempts at passive intravenous (IV) delivery in ICH have …