Turnitin
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Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics
Prokaryotic Argonautes (pAgos) are an emerging class of programmable endonucleases
that are believed to be more flexible than existing CRISPR–Cas systems and have …
that are believed to be more flexible than existing CRISPR–Cas systems and have …
Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases
Advancements in genome editing make possible to exploit the functions of enzymes for
efficient DNA modifications with tremendous potential to treat human genetic diseases …
efficient DNA modifications with tremendous potential to treat human genetic diseases …
Peptide nucleic acid-assisted generation of targeted double-stranded DNA breaks with T7 endonuclease I
Gene-editing technologies have revolutionized biotechnology, but current gene editors
suffer from several limitations. Here, we harnessed the power of gamma-modified peptide …
suffer from several limitations. Here, we harnessed the power of gamma-modified peptide …
A photoresponsive homing endonuclease for programmed DNA cleavage
LA Johnson, RJ Mart, RK Allemann - ACS Synthetic Biology, 2023 - ACS Publications
Homing endonucleases are used in a wide range of biotechnological applications including
gene editing, in gene drive systems, and for the modification of DNA structures, arrays, and …
gene editing, in gene drive systems, and for the modification of DNA structures, arrays, and …
Positive Selection Screens for Programmable Endonuclease Activity Using I-SceI
Positive selection screens are high-throughput assays to characterize novel enzymes from
environmental samples and enrich for more powerful variants from libraries in applications …
environmental samples and enrich for more powerful variants from libraries in applications …
Preliminary Exploration of a DNA Editing Strategy to Treat Cystic Fibrosis using Homology-Independent Targeted Integration and Receptor-Targeted Nanoparticles
C Graham - 2024 - discovery.ucl.ac.uk
Cystic fibrosis (CF) is a common life-limiting disorder. Dysfunctional cystic fibrosis
transmembrane conductance regulator (CFTR) protein hinders mucociliary clearance in the …
transmembrane conductance regulator (CFTR) protein hinders mucociliary clearance in the …
Programmable Control of Protein Activity Via Formation of Biomolecular Condensates in Bacteria
MK Parasa - 2023 - hammer.purdue.edu
Biomolecular condensates or membrane-less organelles are phase separated proteins
and/or other biomolecules that are ubiquitous in eukaryotic cells. While these condensates …
and/or other biomolecules that are ubiquitous in eukaryotic cells. While these condensates …