Directed evolution: methodologies and applications

Y Wang, P Xue, M Cao, T Yu, ST Lane… - Chemical reviews, 2021 - ACS Publications
Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering

ML Sun, TQ Shi, L Lin, R Ledesma-Amaro, XJ Ji - Bioresource Technology, 2022 - Elsevier
Yarrowia lipolytica is recognized as an excellent non-conventional yeast in the field of
biomanufacturing, where it is used as a host to produce oleochemicals, terpenes, organic …

Recent advances in DNA assembly technologies

R Chao, Y Yuan, H Zhao - FEMS yeast research, 2015 - pmc.ncbi.nlm.nih.gov
DNA assembly is one of the most important foundational technologies for synthetic biology
and metabolic engineering. Since the development of the restriction digestion and ligation …

Engineering Shewanella oneidensis enables xylose-fed microbial fuel cell

F Li, Y Li, L Sun, X Li, C Yin, X An, X Chen… - Biotechnology for …, 2017 - Springer
Background The microbial fuel cell (MFC) is a green and sustainable technology for
electricity energy harvest from biomass, in which exoelectrogens use metabolism and …

STSA: A sine Tree-Seed Algorithm for complex continuous optimization problems

J Jiang, M Xu, X Meng, K Li - Physica A: Statistical Mechanics and its …, 2020 - Elsevier
Abstract Tree-Seed Algorithm (TSA) has good performance in solving various optimization
problems. However, it is inevitable to suffer from slow exploitation when solving complex …

DNA assembly techniques for next-generation combinatorial biosynthesis of natural products

RE Cobb, JC Ning, H Zhao - Journal of Industrial Microbiology …, 2014 - academic.oup.com
Natural product scaffolds remain important leads for pharmaceutical development. However,
transforming a natural product into a drug entity often requires derivatization to enhance the …

Applications of computational modeling in metabolic engineering of yeast

EJ Kerkhoven, PJ Lahtvee, J Nielsen - FEMS yeast research, 2015 - academic.oup.com
Synthetic biology and metabolic engineering enable generation of novel cell factories that
efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating …

Enhancing tree-seed algorithm via feed-back mechanism for optimizing continuous problems

J Jiang, X Meng, Y Chen, C Qiu, Y Liu, K Li - Applied Soft Computing, 2020 - Elsevier
Abstract Tree-Seed Algorithm (TSA) is a novel population-based random search algorithm
with its advantages in continuous optimization problems. However, there are some problems …

[BUKU][B] Computational biology and bioinformatics: gene regulation

KC Wong - 2016 - books.google.com
This book presents the latest research in computational biology and bioinformatics, with a
thematic focus on gene regulation. It is designed to be self-contained and comprehensive …

Enhancing the performance of brewing yeasts

M Karabín, L Jelínek, P Kotrba, R Cejnar… - Biotechnology …, 2018 - Elsevier
Beer production is one of the oldest known traditional biotechnological processes, but is
nowadays facing increasing demands not only for enhanced product quality, but also for …