Causes and consequences of snake venom variation

NR Casewell, TNW Jackson, AH Laustsen… - Trends in …, 2020 - cell.com
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …

[HTML][HTML] A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis

CR Ferraz, A Arrahman, C **e, NR Casewell… - Frontiers in ecology …, 2019 - frontiersin.org
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

Complex cocktails: the evolutionary novelty of venoms

NR Casewell, W Wüster, FJ Vonk, RA Harrison… - Trends in ecology & …, 2013 - cell.com
Venoms have evolved on numerous occasions throughout the animal kingdom. These
'biochemical weapon systems' typically function to facilitate, or protect the producing animal …

Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise

J Slagboom, J Kool, RA Harrison… - British journal of …, 2017 - Wiley Online Library
Snake venoms are mixtures of numerous proteinacious components that exert diverse
functional activities on a variety of physiological targets. Because the toxic constituents …

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

FJ Vonk, NR Casewell, CV Henkel… - Proceedings of the …, 2013 - pnas.org
Snakes are limbless predators, and many species use venom to help overpower relatively
large, agile prey. Snake venoms are complex protein mixtures encoded by several …

The biology and evolution of spider venoms

T Lüddecke, V Herzig, BM Von Reumont… - Biological …, 2022 - Wiley Online Library
Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million
years. They are well known for their complex venom systems that are used to overpower …

Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms

NR Casewell, SC Wagstaff, W Wüster… - Proceedings of the …, 2014 - pnas.org
Variation in venom composition is a ubiquitous phenomenon in snakes and occurs both
interspecifically and intraspecifically. Venom variation can have severe outcomes for …

[HTML][HTML] Snake venom metalloproteinases (SVMPs): a structure-function update

OT Olaoba, PK Dos Santos, HS Selistre-de-Araujo… - Toxicon: X, 2020 - Elsevier
Snake venom metalloproteinases (SVMPs) represent a diverse group of multi-domain
proteins with several biological activities such as the ability to induce hemorrhage …

[HTML][HTML] Old World Vipers—a review about snake venom proteomics of Viperinae and their variations

M Damm, BF Hempel, RD Süssmuth - Toxins, 2021 - mdpi.com
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …