Hemeproteins as targets for sulfide species

FM Boubeta, SA Bieza, M Bringas… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Sulfides are endogenous and ubiquitous signaling species that share the
hemeproteins as biochemical targets with O2, nitric oxide, and carbon monoxide. The …

Evolutionary and functional relationships in the truncated hemoglobin family

JP Bustamante, L Radusky, L Boechi… - PLoS computational …, 2016 - journals.plos.org
Predicting function from sequence is an important goal in current biological research, and
although, broad functional assignment is possible when a protein is assigned to a family …

Distribution of cell replication and apoptosis in atherosclerotic plaques of cholesterol-fed rabbits

MM Kockx, GRY De Meyer, J Muhring, H Bult… - Atherosclerosis, 1996 - Elsevier
In human atherosclerosis the development of a cell-poor lipid-rich core is an important
feature of atheromatous plaque formation. The core is characterized by extracellular lipid …

Probing heme active sites of hemoglobin in functional red blood cells using resonance Raman spectroscopy

J Dybas, T Chiura, KM Marzec… - The Journal of Physical …, 2021 - ACS Publications
The UV–vis absorption, Raman imaging, and resonance Raman (rR) spectroscopy methods
were employed to study cyanohemoglobin (HbCN) adducts inside living functional red blood …

Ligand uptake modulation by internal water molecules and hydrophobic cavities in hemoglobins

JP Bustamante, S Abbruzzetti, A Marcelli… - The Journal of …, 2014 - ACS Publications
Internal water molecules play an active role in ligand uptake regulation, since displacement
of retained water molecules from protein surfaces or cavities by incoming ligands can …

Control of distal lysine coordination in a monomeric hemoglobin: A role for heme peripheral interactions

JEM Grundman, LJ Plana, JL Schlessman… - Journal of Inorganic …, 2021 - Elsevier
THB1 is a monomeric truncated hemoglobin (TrHb) found in the cytoplasm of the green alga
Chlamydomonas reinhardtii. The canonical heme coordination scheme in hemoglobins is a …

Distal lysine (de) coordination in the algal hemoglobin THB1: A combined computer simulation and experimental study

LJ Plana, JEM Grundman, DA Estrin… - Journal of Inorganic …, 2021 - Elsevier
THB1 is a monomeric truncated hemoglobin from the green alga Chlamydomonas
reinhardtii. In the absence of exogenous ligands and at neutral pH, the heme group of THB1 …

Second sphere control of spin state: Differential tuning of axial ligand bonds in ferric porphyrin complexes by hydrogen bonding

K Mittra, K Sengupta, A Singha… - Journal of inorganic …, 2016 - Elsevier
An iron porphyrin with a pre-organized hydrogen bonding (H-Bonding) distal architecture is
utilized to avoid the inherent loss of entropy associated with H-Bonding from solvent (water) …

Conformational Flexibility Drives Cold Adaptation in Pseudoalteromonas haloplanktis TAC125 Globins

D Giordano, FM Boubeta, G di Prisco… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Temperature is one of the most important drivers in sha** protein
adaptations. Many biochemical and physiological processes are influenced by temperature …

Interplay of the H-Bond Donor–Acceptor Role of the Distal Residues in Hydroxyl Ligand Stabilization of Thermobifida fusca Truncated Hemoglobin

FP Nicoletti, JP Bustamante, E Droghetti, BD Howes… - Biochemistry, 2014 - ACS Publications
The unique architecture of the active site of Thermobifida fusca truncated hemoglobin (Tf-
trHb) and other globins belonging to the same family has stimulated extensive studies aimed …