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Toward a better understanding of the atypical features of chronic graft-versus-host disease: a report from the 2020 National Institutes of Health Consensus Project …
GDE Cuvelier, M Schoettler, NP Buxbaum… - … and cellular therapy, 2022 - Elsevier
Alloreactive and autoimmune responses after allogeneic hematopoietic cell transplantation
can occur in nonclassical chronic graft-versus-host disease (chronic GVHD) tissues and …
can occur in nonclassical chronic graft-versus-host disease (chronic GVHD) tissues and …
Neurodegeneration in multiple sclerosis
GM Mey, KR Mahajan… - WIREs mechanisms of …, 2023 - Wiley Online Library
Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …
permanent neurologic disability. MS is a heterogeneous demyelinating and …
Serum GFAP and NfL levels differentiate subsequent progression and disease activity in patients with progressive multiple sclerosis
Background and Objectives Neurodegeneration and astrocytic activation are pathologic
hallmarks of progressive multiple sclerosis (MS) and can be quantified by serum …
hallmarks of progressive multiple sclerosis (MS) and can be quantified by serum …
Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis
Sensitive and reliable protein biomarkers are needed to predict disease trajectory and
personalize treatment strategies for multiple sclerosis (MS). Here, we use the highly …
personalize treatment strategies for multiple sclerosis (MS). Here, we use the highly …
Serum neurofilament light chain measurement in MS: hurdles to clinical translation
Measurement of serum neurofilament light chain concentration (sNfL) promises to become a
convenient, cost effective and meaningful adjunct for multiple sclerosis (MS) prognostication …
convenient, cost effective and meaningful adjunct for multiple sclerosis (MS) prognostication …
Association of serum neurofilament light chain levels at disease onset with disability worsening in patients with a first demyelinating multiple sclerosis event not treated …
E Monreal, JI Fernández-Velasco… - JAMA …, 2023 - jamanetwork.com
Importance The value of serum neurofilament light chain (sNfL) levels for predicting long-
term disability in patients with multiple sclerosis (MS) remains controversial. Objective To …
term disability in patients with multiple sclerosis (MS) remains controversial. Objective To …
[HTML][HTML] Neurodegeneration in multiple sclerosis: Symptoms of silent progression, biomarkers and neuroprotective therapy—Kynurenines are important players
D Sandi, Z Fricska-Nagy, K Bencsik, L Vécsei - Molecules, 2021 - mdpi.com
Neurodegeneration is one of the driving forces behind the pathogenesis of multiple sclerosis
(MS). Progression without activity, pathopsychological disturbances (cognitive impairment …
(MS). Progression without activity, pathopsychological disturbances (cognitive impairment …
[HTML][HTML] High or increasing serum NfL is predictive of impending multiple sclerosis relapses
Background One-off serum levels of neurofilament light chain (sNfL) is an established
predictor of emerging disease activity in multiple sclerosis (MS). However, the importance of …
predictor of emerging disease activity in multiple sclerosis (MS). However, the importance of …
Validity of serum neurofilament light chain as a prognostic biomarker of disease activity in multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating and neuroinflammatory disease of the
human central nervous system with complex pathoetiology, heterogeneous presentations …
human central nervous system with complex pathoetiology, heterogeneous presentations …
Serum biomarkers at disease onset for personalized therapy in multiple sclerosis
E Monreal, JI Fernández-Velasco, R Álvarez-Lafuente… - Brain, 2024 - academic.oup.com
The potential for combining serum neurofilament light chain (sNfL) and glial fibrillary acidic
protein (sGFAP) levels to predict worsening disability in multiple sclerosis remains …
protein (sGFAP) levels to predict worsening disability in multiple sclerosis remains …