Evaluating the association of multiple genetic variants with a trait of interest by use of kernel‐
based methods has made a significant impact on how genetic association analyses are …

Hevea brasiliensis (rubber tree) is a large tree species of the Euphorbiaceae family with
inestimable economic importance. Rubber tree breeding programs currently aim to improve …

Linkage disequilibrium (LD) is a fundamental concept in genetics; critical for studying
genetic associations and molecular evolution. However, LD measurements are only reliable …

Background Technological advances are enabling us to collect multimodal datasets at an
increasing depth and resolution while with decreasing labors. Understanding complex …

Currently, most methods for detecting gene–gene interactions (GGIs) in genome-wide
association studies are divided into SNP-based methods and gene-based methods …

Objectives: There is evidence to suggest that asthma pathogenesis is affected by both
genetic and epigenetic variation independently, and there is some evidence to suggest that …

Gene‐gene interactions are increasingly being addressed as a potentially important
contributor to the variability of complex traits. Consequently, attentions have moved beyond …

Over the last few years, case-control genome-wide association studies (GWAS) have proven
to be a successful tool to identify genomic regions associated with complex diseases …

Although immunotherapy has recently proven effective in some cancers, most patients with
metastatic cancer do not benefit from this therapy. A lack of understanding of the …

Background A large amount of research has been devoted to the detection and investigation
of epistatic interactions in genome-wide association studies (GWASs). Most of the literature …