Since techniques for cardiomyocyte isolation were first developed 35years ago, experiments
on single myocytes have yielded great insight into their cellular and sub-cellular physiology …

Lentiviral vectors (LVs) have emerged as potent and versatile vectors for ex vivo or in vivo
gene transfer into dividing and nondividing cells. Robust phenotypic correction of diseases …

Metastatic growth in breast cancer (BC) has been proposed as an exclusive property of
cancer stem cells (CSCs). However, formal proof of their identity as cells of origin of …

MicroRNAs (miRNAs) are noncoding small RNAs that repress protein translation by
targeting specific messenger RNAs. miR-15a and miR-16-1 act as putative tumor …

MicroRNAs play important roles in cell differentiation by acting as translational inhibitors of
specific target genes. Here we show that human granulocytic differentiation is controlled by …

MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression primarily
through translational repression. In erythropoietic (E) culture of cord blood CD34+ progenitor …

Gene therapy is a promising modality for the treatment of inherited and acquired
cardiovascular diseases. The identification of the molecular pathways involved in the …

The interaction between cancer cells and microenvironment has a critical role in tumor
development and progression. Although microRNAs regulate all the major biological …

We describe a pathway by which the master transcription factor PU. 1 regulates human
monocyte/macrophage differentiation. This includes miR-424 and the transcriptional factor …

Angiotensin converting enzyme 2 (ACE2), a newly discovered member of the renin–
angiotensin system (RAS), is a potential therapeutic target for the control of cardiovascular …