Perinatal stroke: map** and modulating developmental plasticity

A Kirton, MJ Metzler, BT Craig, A Hilderley… - Nature Reviews …, 2021 - nature.com
Most cases of hemiparetic cerebral palsy are caused by perinatal stroke, resulting in lifelong
disability for millions of people. However, our understanding of how the motor system …

Noninvasive neuromodulation to promote motor skill gains after perinatal stroke

AJ Hilderley, MJ Metzler, A Kirton - Stroke, 2019 - Am Heart Assoc
The predominant model of dysfunction after perinatal stroke centers on atypical corticospinal
tract (CST) connectivity, as depicted in Figure [A]. CST projections from the motor cortex are …

Transcranial direct current stimulation and constraint-induced therapy in cerebral palsy: a randomized, blinded, sham-controlled clinical trial

B Gillick, T Rich, S Nemanich, CY Chen, J Menk… - European Journal of …, 2018 - Elsevier
We investigated the safety, feasibility, and efficacy of transcranial direct current stimulation
(tDCS) combined with constraint-induced movement therapy (CIMT) in children and young …

Improvements in upper extremity function following intensive training are independent of corticospinal tract organization in children with unilateral spastic cerebral …

KM Friel, CL Ferre, M Brandao, HC Kuo, K Chin… - Frontiers in …, 2021 - frontiersin.org
Background/Objectives: Intensive training of the more affected upper extremity (UE) has
been shown to be effective for children with unilateral spastic cerebral palsy (USCP). Two …

Biological and environmental factors may affect children's executive function through motor and sensorimotor development: preterm birth and cerebral palsy

I Babik, AB Cunha, S Srinivasan - Infant Behavior and Development, 2023 - Elsevier
Disruptive biological and environmental factors may undermine the development of
children's motor and sensorimotor skills. Since the development of cognitive skills, including …

Effect of sensory and motor connectivity on hand function in pediatric hemiplegia

D Gupta, A Barachant, AM Gordon, C Ferre… - Annals of …, 2017 - Wiley Online Library
Objective We tested the hypothesis that somatosensory system injury would more strongly
affect movement than motor system injury in children with unilateral cerebral palsy (USCP) …

Understanding the relationship between brain and upper limb function in children with unilateral motor impairments: a multimodal approach

M Weinstein, D Green, J Rudisch, IM Zielinski… - european journal of …, 2018 - Elsevier
Atypical brain development and early brain injury have profound and long lasting impact on
the development, skill acquisition, and subsequent independence of a child. Heterogeneity …

Corticospinal tract wiring and brain lesion characteristics in unilateral cerebral palsy: determinants of upper limb motor and sensory function

C Simon-Martinez, E Jaspers, L Mailleux… - Neural …, 2018 - Wiley Online Library
Brain lesion characteristics (timing, location, and extent) and the type of corticospinal tract
(CST) wiring have been proposed as determinants of upper limb (UL) motor function in …

A training program using modified joystick-operated ride-on toys to complement conventional upper extremity rehabilitation in children with cerebral palsy: Results …

S Srinivasan, P Kumavor, K Morgan - Bioengineering, 2024 - mdpi.com
The pilot study assessed the utility of a training program using modified, commercially
available dual-joystick-operated ride-on toys to promote unimanual and bimanual upper …

Corpus callosum integrity relates to improvement of upper-extremity function following intensive rehabilitation in children with unilateral spastic cerebral palsy

MT Robert, J Gutterman, CL Ferre… - … and neural repair, 2021 - journals.sagepub.com
Background The corpus callosum (CC) plays an important role in upper extremity (UE)
function. The impact on UE function in children with unilateral spastic cerebral palsy (USCP) …