Recent advances in the label-free characterization of exosomes for cancer liquid biopsy: from scattering and spectroscopy to nanoindentation and nanodevices
Exosomes (EXOs) are nano-sized vesicles secreted by most cell types. They are abundant
in bio-fluids and harbor specific molecular constituents from their parental cells. Due to these …
in bio-fluids and harbor specific molecular constituents from their parental cells. Due to these …
Estimates of natural frequencies for nuclear vibration, and an assessment of the feasibility of selective ultrasound ablation of cancer cells
B Qi, H Zhang, J Zhu, M Wang, C Ma, GM Genin… - Journal of the …, 2024 - Elsevier
Selective ablation of cancer cells by ultrasound would be transformative for cancer therapy,
but has not yet been possible. A key challenge is that cancerous and non-cancerous cells …
but has not yet been possible. A key challenge is that cancerous and non-cancerous cells …
Mechanical Properties of the Extracellular Environment of Human Brain Cells Drive the Effectiveness of Drugs in Fighting Central Nervous System Cancers
The evaluation of nanomechanical properties of tissues in health and disease is of
increasing interest to scientists. It has been confirmed that these properties, determined in …
increasing interest to scientists. It has been confirmed that these properties, determined in …
Sensing red blood cell nano-mechanics: Toward a novel blood biomarker for Alzheimer's disease
Red blood cells (RBCs) are characterized by a remarkable elasticity, which allows them to
undergo very large deformation when passing through small vessels and capillaries. This …
undergo very large deformation when passing through small vessels and capillaries. This …
Changes in spinal cord stiffness in the course of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis
G Pyka-Fościak, J Zemła, GJ Lis, JA Litwin… - Archives of biochemistry …, 2020 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is a commonly used mouse model of
multiple sclerosis, a chronic inflammatory disease of the central nervous system (CNS) …
multiple sclerosis, a chronic inflammatory disease of the central nervous system (CNS) …
A novel method for post-mortem interval estimation based on tissue nano-mechanics
Forensic estimation of post-mortem interval relies on different methods, most of which,
however, have practical limitations or provide insufficient results, still lacking a gold standard …
however, have practical limitations or provide insufficient results, still lacking a gold standard …
Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies
The intrinsically disordered tau protein plays a pivotal role in the pathogenesis of
Alzheimer's disease (AD) and other human tauopathies. Abnormal post-translational …
Alzheimer's disease (AD) and other human tauopathies. Abnormal post-translational …
Efficient spatial sampling for AFM-based cancer diagnostics: a comparison between neural networks and conventional data analysis
Atomic force microscopy (AFM) in spectroscopy mode receives a lot of attention because of
its potential in distinguishing between healthy and cancer tissues. However, the AFM …
its potential in distinguishing between healthy and cancer tissues. However, the AFM …
An evaluation of the objectivity and reproducibility of shear wave elastography in estimating the post-mortem interval: a tissue biomechanical perspective
Cadaveric rigidity—also referred to as rigor mortis—is a valuable source of information for
estimating the time of death, which is a fundamental and challenging task in forensic …
estimating the time of death, which is a fundamental and challenging task in forensic …
[HTML][HTML] Sensing Biomechanical Alterations in Red Blood Cells of Type 1 Diabetes Patients: Potential Markers for Microvascular Complications
In physiological conditions, red blood cells (RBCs) demonstrate remarkable deformability,
allowing them to undergo considerable deformation when passing through the …
allowing them to undergo considerable deformation when passing through the …