Mechanism and applications of CRISPR/Cas-9-mediated genome editing

M Asmamaw, B Zawdie - Biologics: targets and therapy, 2021 - Taylor & Francis
Clustered regularly interspaced short palindromic repeat (CRISPR) and their associated
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …

CRISPR-Cas for genome editing: classification, mechanism, designing and applications

S Bhatia, SK Yadav - International Journal of Biological Macromolecules, 2023 - Elsevier
Clustered regularly interspersed short pallindromic repeats (CRISPR) and CRISPR
associated proteins (Cas) system (CRISPR-Cas) came into light as prokaryotic defence …

Advancing genome editing with artificial intelligence: opportunities, challenges, and future directions

S Dixit, A Kumar, K Srinivasan… - … in Bioengineering and …, 2024 - frontiersin.org
Clustered regularly interspaced short palindromic repeat (CRISPR)-based genome editing
(GED) technologies have unlocked exciting possibilities for understanding genes and …

The post-GWAS era: from association to function

MD Gallagher, AS Chen-Plotkin - The American Journal of Human …, 2018 - cell.com
During the past 12 years, genome-wide association studies (GWASs) have uncovered
thousands of genetic variants that influence risk for complex human traits and diseases. Yet …

Genome edited crops touch the market: a view on the global development and regulatory environment

J Menz, D Modrzejewski, F Hartung… - Frontiers in plant …, 2020 - frontiersin.org
Products of genome editing as the most promising “New Plant Breeding Technology”(NPBT)
have made the transition from the lab to the market in a short time. Globally, research …

[BOK][B] Human genome editing: science, ethics, and governance

National Academies of Sciences, Medicine… - 2017 - books.google.com
Genome editing is a powerful new tool for making precise alterations to an organism's
genetic material. Recent scientific advances have made genome editing more efficient …

[HTML][HTML] Principles of CRISPR-Cas9 technology: Advancements in genome editing and emerging trends in drug delivery

AAA Aljabali, M El-Tanani, MM Tambuwala - Journal of Drug Delivery …, 2024 - Elsevier
The rapid advancement of CRISPR-Cas9 technology has instigated a profound
transformation in genome editing with significant implications for fields like health …

Application of gene editing for climate change in agriculture

NG Karavolias, W Horner, MN Abugu… - Frontiers in Sustainable …, 2021 - frontiersin.org
Climate change imposes a severe threat to agricultural systems, food security, and human
nutrition. Meanwhile, efforts in crop and livestock gene editing have been undertaken to …

[HTML][HTML] Gene therapy for retinal degenerative diseases: progress, challenges, and future directions

S Drag, F Dotiwala… - … Ophthalmology & Visual …, 2023 - tvst.arvojournals.org
Since long before the first approval of gene therapy for retinal disease, ocular gene therapy
has captured the hopes of patients, clinicians, and scientists alike. Indeed, the retina …

[HTML][HTML] The genome editing revolution

AM Khalil - Journal of genetic engineering and biotechnology, 2020 - Elsevier
Background Development of efficient strategies has always been one of the great
perspectives for biotechnologists. During the last decade, genome editing of different …