When force met fluorescence: single-molecule manipulation and visualization of protein–DNA interactions
Myriad DNA-binding proteins undergo dynamic assembly, translocation, and conformational
changes while on DNA or alter the physical configuration of the DNA substrate to control its …
changes while on DNA or alter the physical configuration of the DNA substrate to control its …
The mutation R107Q alters mtSSB ssDNA compaction ability and binding dynamics
Mitochondrial single-stranded DNA-binding protein (mtSSB) is essential for mitochondrial
DNA (mtDNA) replication. Recently, several mtSSB variants have been associated with …
DNA (mtDNA) replication. Recently, several mtSSB variants have been associated with …
[HTML][HTML] Life under tension: the relevance of force on biological polymers
Optical tweezers have elucidated numerous biological processes, particularly by enabling
the precise manipulation and measurement of tension. One question concerns the biological …
the precise manipulation and measurement of tension. One question concerns the biological …
[PDF][PDF] Biophysics Reports
MTJ Halma, L Xu - 2024 - researchgate.net
Optical tweezers have elucidated numerous biological processes, particularly by enabling
the precise manipulation and measurement of tension. One question concerns the biological …
the precise manipulation and measurement of tension. One question concerns the biological …
Characterizing Multi-Modal Interactions of Single-Stranded Nucleic Acid Binding Proteins From T4 Bacteriophage and the LINE-1 Retrotransposon
BA Cashen - 2024 - search.proquest.com
Single molecule force spectroscopy is a powerful tool for characterizing protein-DNA
interactions. DNA stretching in optical tweezers provides high resolution measurements of …
interactions. DNA stretching in optical tweezers provides high resolution measurements of …