Radiochemistry for positron emission tomography

J Rong, A Haider, TE Jeppesen, L Josephson… - Nature …, 2023‏ - nature.com
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022‏ - mdpi.com
Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images

B Zhao, T Li, Z Fan, Y Yang, J Shu, X Yang, X Wang… - Science, 2023‏ - science.org
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …

The multiple roles of life stress in metabolic disorders

M Kivimäki, A Bartolomucci, I Kawachi - Nature Reviews Endocrinology, 2023‏ - nature.com
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Neutrophils as regulators of cardiovascular inflammation

C Silvestre-Roig, Q Braster, A Ortega-Gomez… - Nature Reviews …, 2020‏ - nature.com
Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular
disease. However, studies in the past decade have demonstrated the important functions of …

Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes

V Regitz-Zagrosek, C Gebhard - Nature Reviews Cardiology, 2023‏ - nature.com
Despite a growing body of evidence, the distinct contributions of biological sex and the
sociocultural dimension of gender to the manifestations and outcomes of ischaemic heart …

Effects of stress on the development and progression of cardiovascular disease

M Kivimäki, A Steptoe - Nature Reviews Cardiology, 2018‏ - nature.com
Cardiovascular disease remains the leading cause of disease burden globally, which
underlies the continuing need to identify new complementary targets for prevention. Over the …

[HTML][HTML] Uncertainty and stress: Why it causes diseases and how it is mastered by the brain

A Peters, BS McEwen, K Friston - Progress in neurobiology, 2017‏ - Elsevier
The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Biological embedding of childhood adversity: from physiological mechanisms to clinical implications

AE Berens, SKG Jensen, CA Nelson - BMC medicine, 2017‏ - Springer
Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …

Sex and gender in cardiovascular medicine: presentation and outcomes of acute coronary syndrome

A Haider, S Bengs, J Luu, E Osto… - European heart …, 2020‏ - academic.oup.com
Although health disparities in women presenting with acute coronary syndrome (ACS) have
received growing attention in recent years, clinical outcomes from ACS are still worse for …