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SGLT2 inhibitors: from glucose-lowering to cardiovascular benefits
An increasing number of individuals are at high risk of type 2 diabetes (T2D) and its
cardiovascular complications, including heart failure (HF), chronic kidney disease (CKD) …
cardiovascular complications, including heart failure (HF), chronic kidney disease (CKD) …
Comparative cardiovascular outcomes in type 2 diabetes patients taking dapagliflozin versus empagliflozin: a nationwide population-based cohort study
Background Sodium-glucose co-transporter-2 inhibitors displayed cardiovascular benefits in
type 2 diabetes mellitus in previous studies; however, there were some heterogeneities …
type 2 diabetes mellitus in previous studies; however, there were some heterogeneities …
IL‑37 suppresses macrophage ferroptosis to attenuate diabetic atherosclerosis via the NRF2 pathway
J Xu, X Han, N **a, Q Zhao… - Experimental and …, 2023 - spandidos-publications.com
IL‑37 is a newly discovered inflammatory factor. However, the protective effect and
underlying mechanisms of IL‑37 on atherosclerosis remain unclear. In the present study, IL …
underlying mechanisms of IL‑37 on atherosclerosis remain unclear. In the present study, IL …
[HTML][HTML] Mitigating Vascular Inflammation by Mimicking AIBP Mechanisms: A New Therapeutic End for Atherosclerotic Cardiovascular Disease
JD Kim, A Jain, L Fang - International Journal of Molecular Sciences, 2024 - mdpi.com
Atherosclerosis, characterized by the accumulation of lipoproteins and lipids within the
vascular wall, underlies a heart attack, stroke, and peripheral artery disease. Endothelial …
vascular wall, underlies a heart attack, stroke, and peripheral artery disease. Endothelial …
Danggui Liuhuang Decoction ameliorates endothelial dysfunction by inhibiting the JAK2/STAT3 mediated inflammation
Y Xu, W Sha, J Lu, S Yu, X **, C Chen, G Ge… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance Vascular endothelial dysfunction (VED) is recognized as a
key triggering diabetic vascular complications. Danggui Liuhuang Decoction (DGLHD) has …
key triggering diabetic vascular complications. Danggui Liuhuang Decoction (DGLHD) has …
[HTML][HTML] Hutchinson-Gilford progeria syndrome mice display accelerated arterial thrombus formation and increased platelet reactivity
Abstract Introduction Hutchinson-Gilford Progeria Syndrome (HGPS) is an ultra-rare
premature aging genetic disorder caused by a point mutation in the lamin A gene, LMNA …
premature aging genetic disorder caused by a point mutation in the lamin A gene, LMNA …
Protective Mechanisms of SGLTi in Ischemic Heart Disease
L Liao, T Wang, L Zhang, Y Wei, X Fan - Journal of Cardiovascular …, 2024 - Springer
Ischemic heart disease (IHD) is a common clinical cardiovascular disease with high
morbidity and mortality. Sodium glucose cotransporter protein inhibitor (SGLTi) is a novel …
morbidity and mortality. Sodium glucose cotransporter protein inhibitor (SGLTi) is a novel …
Initial systolic blood pressure associates with systemic inflammation, myocardial injury, and outcomes in patients with acute coronary syndromes
Aims Outcomes after acute coronary syndromes (ACS) are determined by baseline risk
profiles, including initial systolic blood pressure (sBP) levels. Herein, we aimed to …
profiles, including initial systolic blood pressure (sBP) levels. Herein, we aimed to …