Recent advances in the development and application of peptide self-assemblies in infection control

T Ge, X Hu, M Liao, F Zhou, JR Lu - Current Opinion in Colloid & Interface …, 2023 - Elsevier
Peptide self-assemblies display distinct physical and structural transitions, ranging from the
early small assemblies, or oligomers, to long nanosheets, nanobelts, nanotubes, and …

[HTML][HTML] Sha** the future of antimicrobial therapy: harnessing the power of antimicrobial peptides in biomedical applications

AK Tripathi, J Singh, R Trivedi, P Ranade - Journal of Functional …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules
with the potential to combat infections associated with medical implants and biomaterials …

A bacterially engineered macrophage sponge as a neutralization decoy to treat bacterial infection

C Gao, CHT Kwong, M Tang, J Liu, H Kam, S Li… - Matter, 2023 - cell.com
Antibiotic-resistant strains have emerged, and endotoxins vary greatly in their structural
motifs across bacterial species, limiting the clearance efficiency of structure-specific anti …

Identification of a 10-mer peptide from the death domain of MyD88 which attenuates inflammation and insulin resistance and improves glucose metabolism

M Ali, T Kumari, A Gupta, S Akhtar… - Biochemical …, 2024 - portlandpress.com
Insulin resistance (IR) is the key pathophysiological cause of type 2 diabetes, and
inflammation has been implicated in it. The death domain (DD) of the adaptor protein …

Short peptides based on the conserved regions of MIEN1 protein exhibit anticancer activity by targeting the MIEN1 signaling pathway

AK Tripathi, PP Desai, A Tyagi, JB Lampe… - Journal of Biological …, 2024 - jbc.org
Migration and invasion enhancer 1 (MIEN1) overexpression characterizes several cancers
and facilitates cancer cell migration and invasion. Leveraging conserved immunoreceptor …

[HTML][HTML] Innovative Strategies and Methodologies in Antimicrobial Peptide Design

DP Verma, AK Tripathi, AK Thakur - Journal of Functional Biomaterials, 2024 - mdpi.com
Multiple lines of research have led to the hypothesis that antimicrobial peptides (AMPs) are
an important component of the innate immune response, playing a vital role in the defense …

[HTML][HTML] Role of anti-cancer peptides as immunomodulatory agents: potential and design strategy

AK Tripathi, JK Vishwanatha - Pharmaceutics, 2022 - mdpi.com
The usage of peptide-based drugs to combat cancer is gaining significance in the
pharmaceutical industry. The collateral damage caused to normal cells due to the use of …

Generating a Peptide Library Using the Repeats of Amino Acid Scaffolds Created by Sliding the Framework of a 7-mer Human Chemerin Segment and Discovery of …

S Akhtar, MM Ansari, RD Verma, J Sharma… - Journal of Medicinal …, 2024 - ACS Publications
The quest for new approaches for generating novel bioactive designer proteins/peptides has
continued with their success in various biomedical applications. Previously, we designed a …

[HTML][HTML] A peptide derived from the amino terminus of leptin improves glucose metabolism and energy homeostasis in myotubes and db/db mice

M Ali, A Gupta, RD Verma, S Akhtar… - Journal of Biological …, 2024 - Elsevier
Leptin is an adipokine, which plays key roles in regulation of glucose metabolism and
energy homeostasis. Therefore, identification of a short peptide from leptin which improves …

The Characterization, Biological Activities, and Potential Applications of the Antimicrobial Peptides Derived from Bacillus spp.: A Comprehensive Review

J Zhang, X Yang, J Qiu, W Zhang, J Yang… - Probiotics and …, 2024 - Springer
This paper provides a comprehensive review of antimicrobial peptides (AMPs) derived from
Bacillus spp. The classification and structure of Bacillus-derived AMPs encompass a diverse …