Design and application in delivery system of intranasal antidepressants
J Xu, J Tao, J Wang - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …
Nano carrier drug delivery systems for the treatment of neuropsychiatric disorders: Advantages and limitations
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …
people. Various drugs are used for its treatment, although no effective therapy has been …
Collagen nanofiber containing silver nanoparticles for improved wound-healing applications
Electrospun nanofibers showing great promise for fabricating nanostructured materials
might help to improve the quality of wound care. The present study aimed to investigate the …
might help to improve the quality of wound care. The present study aimed to investigate the …
Intranasal delivery of functionalized polymeric nanomaterials to the brain
Intravenous delivery of nanomaterials containing therapeutic agents and various cargos for
treating neurological disorders is often constrained by low delivery efficacy due to difficulties …
treating neurological disorders is often constrained by low delivery efficacy due to difficulties …
Recent advances in drug delivery nanocarriers incorporated in temperature-sensitive Pluronic F-127–A critical review
New polymeric systems are constantly developed for novel biomedical applications.
Pluronic F127 (PF127) is a tri-block copolymer with surface-active properties. It comprises a …
Pluronic F127 (PF127) is a tri-block copolymer with surface-active properties. It comprises a …
Tramadol hydrochloride: pharmacokinetics, pharmacodynamics, adverse side effects, co-administration of drugs and new drug delivery systems
Tramadol hydrochloride (TrHC) is a synthetic analgesic drug exhibiting opioid and non-
opioid properties, acting mainly on the central nervous system. It has been mostly used to …
opioid properties, acting mainly on the central nervous system. It has been mostly used to …
Lipid and polymeric nanoparticles: successful strategies for nose-to-Brain drug delivery in the treatment of depression and anxiety disorders
M Alberto, AC Paiva-Santos, F Veiga, PC Pires - Pharmaceutics, 2022 - mdpi.com
Intranasal administration has gained an increasing interest for brain drug delivery since it
allows direct transport through neuronal pathways, which can be quite advantageous for …
allows direct transport through neuronal pathways, which can be quite advantageous for …
Polysaccharide-based hydrogels for drug delivery and wound management: a review
ABSTRACT Introduction Polysaccharide-based hydrogels (PBHs) offer several advantages
over their synthetic counterparts. Their natural origin contributes to their nontoxicity, high …
over their synthetic counterparts. Their natural origin contributes to their nontoxicity, high …
In situ-based gels for nose to brain delivery for the treatment of neurological diseases
BA Aderibigbe - Pharmaceutics, 2018 - mdpi.com
In situ-based gel drug delivery systems that can bypass the blood-brain barrier, deliver the
therapeutics to the desired site, reduce peripheral toxicity and control drug release kinetics …
therapeutics to the desired site, reduce peripheral toxicity and control drug release kinetics …
Chitosan gel-embedded moxifloxacin niosomes: an efficient antimicrobial hybrid system for burn infection
The purpose of this study was to prepare and characterize a hybrid system of moxifloxacin
loaded niosomes incorporated into chitosan gel as a potential carrier for topical …
loaded niosomes incorporated into chitosan gel as a potential carrier for topical …