For complete absorption and good bioavailability of orally administered drug, the drug must
be dissolved in gastric fluids. Dissolution of drug is the rate-controlling step which …

Most of the drugs in the developmental pipeline are emerging from the High-Throughput
Screening methodology resulting in increased molecular weights and thus consequential …

A facile and simplified method was developed for the synthesis of 3D cubic mesoporous
SBA-16 with both a spherical morphology and controllable pore size. The addition of CTAB …

The goal of the present study was to compare the drug release properties and stability of the
nanoporous silica with different pore architectures as a matrix for improved delivery of poorly …

Gliclazide is practically insoluble in water. In order to improve the drug dissolution rate,
cogrinding method was used as an approach to prepare gliclazide coground/solid …

The objective of this work was to study dissolution enhancement efficiency and solid
dispersion formation ability of hydrophilic swellable polymers such as sodium carboxymethyl …

This investigation was undertaken to unveil the controlled drug delivery and preclinical anti-
hypertensive potential of a novel interpenetrating biopolymer-based network of karaya gum …

The objective of the study was enhancement of dissolution of poorly soluble carvedilol by
solid dispersions (SDs) with Gelucire 50/13 using solvent evaporation method. The solubility …

The aim of the present study was to enhance the dissolution rate of valdecoxib using its solid
dispersions (SDs) with polyethylene glycol (PEG) 4000. The phase solubility behavior of …

Solid dispersions in water-soluble carriers have attracted considerable interest as a means
of improving the dissolution rate, and hence possibly bioavailability, of a range of …