[HTML][HTML] Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z **ao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications

Z Sun, D Zhu, H Zhao, J Liu, P He, X Luan, H Hu… - Journal of …, 2023 - Springer
Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to
their unique chemical, physical, and biological properties and functions. In this …

Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

High rapamycin-loaded hollow mesoporous Prussian blue nanozyme targets lesion area of spinal cord injury to recover locomotor function

K Shen, X Li, G Huang, Z Yuan, B **e, T Chen, L He - Biomaterials, 2023 - Elsevier
Scavenging free radicals and reducing inflammatory reaction to relieve the secondary
damage are important issues in the spinal cord injury (SCI) therapeutic strategy. Nanozymes …

Biphasic drug release from electrospun structures

J Zhou, P Wang, DG Yu, Y Zhu - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction Biphasic release, as a special drug-modified release profile that combines
immediate and sustained release, allows fast therapeutic action and retains blood drug …

Biomaterial-based regenerative therapeutic strategies for spinal cord injury

K Chen, W Yu, G Zheng, Z Xu, C Yang, Y Wang… - NPG Asia …, 2024 - nature.com
As one of the most intractable neurological diseases, spinal cord injury (SCI) often leads to
permanent neurological impairment in patients. Unfortunately, due to the complex …

Peptide hydrogels as immunomaterials and their use in cancer immunotherapy delivery

N Falcone, M Ermis, DG Tamay… - Advanced …, 2023 - Wiley Online Library
Peptide‐based hydrogel biomaterials have emerged as an excellent strategy for immune
system modulation. Peptide‐based hydrogels are supramolecular materials that self …

[HTML][HTML] The role of biomaterials in peripheral nerve and spinal cord injury: a review

B Kaplan, S Levenberg - International journal of molecular sciences, 2022 - mdpi.com
Peripheral nerve and spinal cord injuries are potentially devastating traumatic conditions
with major consequences for patients' lives. Severe cases of these conditions are currently …

The martini model in materials science

R Alessandri, F Grünewald, SJ Marrink - Advanced Materials, 2021 - Wiley Online Library
The Martini model, a coarse‐grained force field initially developed with biomolecular
simulations in mind, has found an increasing number of applications in the field of soft …