Background A watch-and-wait approach for patients with clinical complete response to
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal …

The standard of care in locally advanced rectal cancer is neoadjuvant chemoradiation
(nCRT) followed by radical surgery. Response to nCRT varies among patients and …

This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

Importance Assessing clinical tumor response following completion of total neoadjuvant
therapy (TNT) in patients with locally advanced rectal cancer is paramount to select patients …

Purpose To investigate the value of T2-weighted–based radiomics compared with
qualitative assessment at T2-weighted imaging and diffusion-weighted (DW) imaging for …

Background Preoperative chemoradiotherapy with infusional fluorouracil, total mesorectal
excision surgery, and postoperative chemotherapy with fluorouracil was established by the …

Objective For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy
selection following surgery remains a major clinical dilemma. Here, we investigated the …

Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal
cancer. Adjuvant chemotherapy is usually used for distant control. However, not all patients …

Background Deep learning (DL) models can potentially improve prognostication of rectal
cancer but have not been systematically assessed. Purpose To develop and validate an MRI …