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Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy
Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on
the surface of the brain. Historically considered a result of head trauma, recent evidence …
the surface of the brain. Historically considered a result of head trauma, recent evidence …
Cellular infiltration in traumatic brain injury
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
Traumatic axonal injury: mechanisms and translational opportunities
Traumatic axonal injury (TAI) is an important pathoanatomical subgroup of traumatic brain
injury (TBI) and a major driver of mortality and functional impairment. Experimental models …
injury (TBI) and a major driver of mortality and functional impairment. Experimental models …
Crosstalk between neuroinflammation and oxidative stress in epilepsy
T Fabisiak, M Patel - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …
have begun to receive considerable attention in recent years. However, these concepts are …
Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines
S Gyoneva, RM Ransohoff - Trends in pharmacological sciences, 2015 - cell.com
Traumatic brain injury (TBI) affects millions of people worldwide every year. The primary
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …
Molecular and cellular mechanisms of pulmonary fibrosis
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury
Background Previous studies have shown beneficial effects of mesenchymal stem cell
(MSC) transplantation in central nervous system (CNS) injuries, including traumatic brain …
(MSC) transplantation in central nervous system (CNS) injuries, including traumatic brain …
Acute inflammatory response following increased blood-brain barrier permeability induced by focused ultrasound is dependent on microbubble dose
Rationale: Focused ultrasound (FUS), in conjunction with circulating microbubbles (MBs),
can be used to transiently increase the permeability of the blood-brain barrier (BBB) in a …
can be used to transiently increase the permeability of the blood-brain barrier (BBB) in a …
Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury
H Zhu, C Bian, J Yuan, W Chu, X **ang, F Chen… - Journal of …, 2014 - Springer
Background Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …
Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model
Objective Traumatic brain injury (TBI) is a recognized risk factor for later development of
neurodegenerative disease. However, the mechanisms contributing to neurodegeneration …
neurodegenerative disease. However, the mechanisms contributing to neurodegeneration …