Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy

E Edlmann, S Giorgi-Coll, PC Whitfield… - Journal of …, 2017 - Springer
Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on
the surface of the brain. Historically considered a result of head trauma, recent evidence …

Cellular infiltration in traumatic brain injury

A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf… - Journal of …, 2020 - Springer
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

Traumatic axonal injury: mechanisms and translational opportunities

CS Hill, MP Coleman, DK Menon - Trends in neurosciences, 2016 - cell.com
Traumatic axonal injury (TAI) is an important pathoanatomical subgroup of traumatic brain
injury (TBI) and a major driver of mortality and functional impairment. Experimental models …

Crosstalk between neuroinflammation and oxidative stress in epilepsy

T Fabisiak, M Patel - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

S Gyoneva, RM Ransohoff - Trends in pharmacological sciences, 2015 - cell.com
Traumatic brain injury (TBI) affects millions of people worldwide every year. The primary
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …

Molecular and cellular mechanisms of pulmonary fibrosis

NW Todd, IG Luzina, SP Atamas - Fibrogenesis & tissue repair, 2012 - Springer
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury

R Zhang, Y Liu, K Yan, L Chen, XR Chen, P Li… - Journal of …, 2013 - Springer
Background Previous studies have shown beneficial effects of mesenchymal stem cell
(MSC) transplantation in central nervous system (CNS) injuries, including traumatic brain …

Acute inflammatory response following increased blood-brain barrier permeability induced by focused ultrasound is dependent on microbubble dose

D McMahon, K Hynynen - Theranostics, 2017 - pmc.ncbi.nlm.nih.gov
Rationale: Focused ultrasound (FUS), in conjunction with circulating microbubbles (MBs),
can be used to transiently increase the permeability of the blood-brain barrier (BBB) in a …

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

H Zhu, C Bian, J Yuan, W Chu, X **ang, F Chen… - Journal of …, 2014 - Springer
Background Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model

BC Mouzon, C Bachmeier, A Ferro, JO Ojo… - Annals of …, 2014 - Wiley Online Library
Objective Traumatic brain injury (TBI) is a recognized risk factor for later development of
neurodegenerative disease. However, the mechanisms contributing to neurodegeneration …