Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

Lung cancer (LC) is a heterogeneous disease with high malignant degree, rapid growth,
and early metastasis. The clinical outcomes of LC patients are generally poor due to the …

Cardiovascular diseases are among the leading causes of death worldwide. Reactive
oxygen species (ROS) can act as damaging molecules but also represent central hubs in …

Cardiovascular diseases (CVDs) have diverse physiopathological mechanisms with
interconnected oxidative stress and inflammation as one of the common etiologies which …

Depression is a multifactorial disease with unknown etiology affecting globally. It's the
second most significant reason for infirmity in 2020, affecting about 50 million people …

Long non-coding RNAs were once considered as “junk” RNA produced by aberrant DNA
transcription. They are now understood to play central roles in diverse cellular processes …

Oxidative genome damage is an unavoidable consequence of cellular metabolism. It arises
at gene regulatory elements by epigenetic demethylation during transcriptional activation …

Transcription is a highly regulated process, and stress-induced changes in gene
transcription have been shown to play a major role in stress responses and adaptation …

Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite
the increasing amount of literature data, the least understood. Given the involvement of …

Increased production of reactive oxygen species (ROS) significantly contributed to the
pathogenesis of acute myocardial infarction (AMI). Recent studies suggest that hypoxia …