Toxicity of mercury: Molecular evidence

L Yang, Y Zhang, F Wang, Z Luo, S Guo, U Strähle - Chemosphere, 2020 - Elsevier
Minamata disease in Japan and the large-scale poisoning by methylmercury (MeHg) in Iraq
caused wide public concerns about the risk emanating from mercury for human health …

Pharmaceuticals in the aquatic environment: a critical review of the evidence for health effects in fish

J Corcoran, MJ Winter, CR Tyler - Critical reviews in toxicology, 2010 - Taylor & Francis
The authors review the current data on the presence and reported biological effects in fish of
some of the most commonly detected pharmaceuticals in the aquatic environment; namely …

Ovarian aromatase and estrogens: a pivotal role for gonadal sex differentiation and sex change in fish

Y Guiguen, A Fostier, F Piferrer, CF Chang - General and comparative …, 2010 - Elsevier
The present review focuses on the roles of estrogens and aromatase (Cyp19a1a), the
enzyme needed for their synthesis, in fish gonadal sex differentiation. Based on the recent …

A comprehensive review on environmental toxicity of azole compounds to fish

J Bhagat, N Singh, N Nishimura, Y Shimada - Chemosphere, 2021 - Elsevier
Background Azoles are considered as one of the most efficient fungicides for the treatment
of humans, animals, and plant fungal pathogens. They are of significant clinical importance …

Occurrence, fate and ecological risk of five typical azole fungicides as therapeutic and personal care products in the environment: a review

ZF Chen, GG Ying - Environment International, 2015 - Elsevier
Azole fungicides are widely used to treat fungal infection in human. After application, these
chemicals may reach to the receiving environment via direct or indirect discharge of …

Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish

K Cheshenko, F Pakdel, H Segner, O Kah… - General and comparative …, 2008 - Elsevier
Many natural and synthetic compounds present in the environment exert a number of
adverse effects on the exposed organisms, leading to endocrine disruption, for which they …

Evaluation of acute and developmental effects of difenoconazole via multiple stage zebrafish assays

X Mu, S Pang, X Sun, J Gao, J Chen, X Chen, X Li… - Environmental …, 2013 - Elsevier
Zebrafish, during embryo, larvae and adult stages were selected to investigate the potential
environmental risk and aquatic toxicity of a widely used fungicide, difenoconazole. In …

Adverse outcome pathways: a concise introduction for toxicologists

M Vinken, D Knapen, L Vergauwen, JG Hengstler… - Archives of …, 2017 - Springer
Adverse outcome pathways (AOPs) are designed to provide a clear-cut mechanistic
representation of critical toxicological effects that propagate over different layers of biological …

Mercury‐induced reproductive impairment in fish

KL Crump, VL Trudeau - Environmental Toxicology and …, 2009 - Wiley Online Library
Mercury is a potent neurotoxin, and increasing levels have led to concern for human and
wildlife health in many regions of the world. During the past three decades, studies in fish …

Effects of pharmaceuticals present in aquatic environment on Phase I metabolism in fish

V Burkina, V Zlabek, G Zamaratskaia - Environmental toxicology and …, 2015 - Elsevier
The fate of pharmaceuticals in aquatic environments is an issue of concern. Current
evidence indicates that the risks to fish greatly depend on the nature and concentrations of …