Simple Summary The mitogen-activated protein kinase/extracellular signal-regulated kinase
(MAPK/ERK) signaling pathway is frequently activated in liver cancer, which is one of the …

Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

The treatment of low-risk primary prostate cancer entails active surveillance only, while high-
risk disease requires multimodal treatment including surgery, radiation therapy, and …

Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …

The rates of obesity and diabetes are increasing worldwide, whereas the age of onset for
both obesity and diabetes are decreasing steadily. Obesity and diabetes are associated with …

Soy is a hotly debated and widely discussed topic in the field of nutrition. However, health
practitioners may be ill-equipped to counsel clients and patients about the use of soyfoods …

Several components of the GH axis are involved in tumor progression, and GH-induced
intracellular signaling has been strongly associated with breast cancer susceptibility in …

Despite a strong preclinical rationale for targeting the insulin-like growth factor (IGF) axis in
cancer, clinical studies of IGF-1 receptor (IGF-1R)-targeted monotherapies have been …

Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …