Background: Inbreeding continues to account for a significant proportion of marriages
among the Arab populations. Consanguinity is recognized in many studies as a significant …

Post-transcriptional tRNA modifications are numerous and require a large set of highly
conserved enzymes in humans and other organisms. In yeast, the loss of many …

Background Diagnostic testing for primary ciliary dyskinesia (PCD) started in 2013 in
Palestine. We aimed to describe the diagnostic, genetic and clinical spectrum of the …

Background/Aim Consanguinity represents a biological relationship between two
individuals. In clinical genetics, it specifically refers to the marriage between individuals who …

Background and aims Genetic knowledge and familiarity among the population represent
the lane toward effective participation in social decisions regarding genetic issues. This …

Progressive childhood encephalopathy is an etiologically heterogeneous condition
characterized by progressive central nervous system dysfunction in association with a broad …

Background Of our 1400 exome-studied patients, 67% originate from consanguineous
families.∼ 80% suffer from variable degree of intellectual disability (ID). The search for …

Objectives In Gaza Strip, Palestine, β-thalassemia is a major public health problem where
more than 300 β-thalassemia major (βTM) patients are currently being managed at …

Exacerbated by 9 years of conflict and displacement, child marriage among Syrian refugees
appears to be increasing, while in Gaza, the noticeable reduction in child brides over the …

Background Osteogenesis imperfecta (OI) is a heterogeneous hereditary connective tissue
disorder clinically hallmarked by increased susceptibility to bone fractures. Methods We …