Neural mechanisms of addiction: the role of reward-related learning and memory
Addiction is a state of compulsive drug use; despite treatment and other attempts to control
drug taking, addiction tends to persist. Clinical and laboratory observations have converged …
drug taking, addiction tends to persist. Clinical and laboratory observations have converged …
Addiction, dopamine, and the molecular mechanisms of memory
Joshua D. Berke* § and Steven E. Hyman*†‡* Section on Molecular Plasticity National
Institute of Neurological Disorders and Stroke locomotor activity. Psychostimulants also tend …
Institute of Neurological Disorders and Stroke locomotor activity. Psychostimulants also tend …
Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus
The present study demonstrates that chronic, but not acute, adminstration of several different
classes of antidepressants, including serotonin-and norepinephrine-selective reuptake …
classes of antidepressants, including serotonin-and norepinephrine-selective reuptake …
Addiction: a disease of learning and memory
SE Hyman - American Journal of Psychiatry, 2005 - Am Psychiatric Assoc
If neurobiology is ultimately to contribute to the development of successful treatments for
drug addiction, researchers must discover the molecular mechanisms by which drug …
drug addiction, researchers must discover the molecular mechanisms by which drug …
Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term …
JF Guzowski, GL Lyford, GD Stevenson… - Journal of …, 2000 - Soc Neuroscience
It is widely believed that the brain processes information and stores memories by modifying
and stabilizing synaptic connections between neurons. In experimental models of synaptic …
and stabilizing synaptic connections between neurons. In experimental models of synaptic …
Dopamine receptor signaling
KA Neve, JK Seamans… - Journal of receptors and …, 2004 - Taylor & Francis
The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has
shared signaling properties that contribute to the definition of the receptor class, although …
shared signaling properties that contribute to the definition of the receptor class, although …
Structure and function of dopamine receptors
D Vallone, R Picetti, E Borrelli - Neuroscience & biobehavioral reviews, 2000 - Elsevier
Dopamine (DA) is the most abundant catecholamine in the brain. The involvement and
importance of DA as a neurotransmitter in the regulation of different physiological functions …
importance of DA as a neurotransmitter in the regulation of different physiological functions …
The basal ganglia
AM Graybiel - Current biology, 2000 - cell.com
The basal ganglia, said Kinnear-Wilson in the 1920s, have all the clarity of a dark basement.
And so it has remained for the better part of a century. There are now major new ideas about …
And so it has remained for the better part of a century. There are now major new ideas about …
Invited review c-Fos as a transcription factor: a stressful (re) view from a functional map
KJ Kovács - Neurochemistry international, 1998 - Elsevier
This article summarizes the achievements that have been accumulated about the role of c-
Fos as a transcription factor and as a functional marker of activated neurons. Since its …
Fos as a transcription factor and as a functional marker of activated neurons. Since its …