Need assessment for HIV drug resistance testing and landscape of current and future Technologies in Low-and middle-income countries

N Parkin, PR Harrigan, S Inzaule… - PLOS Global Public …, 2023 - journals.plos.org
Resistance to antiretroviral drugs used to treat HIV is an important and evolving concern,
particularly in low-and middle-income countries (LMICs) which have been impacted to the …

A minimally instrumented method for the detection of rifampicin resistance-causing mutations in Mycobacterium tuberculosis utilizing lateral flow readout

A Chauhan, S SivaKumar, B Toley - 2024 - chemrxiv.org
Genotypic methods for the determination of antimicrobial resistance in Mycobacterium
tuberculosis (M. tb) require expensive instruments, which limits their availability in peripheral …

Implementation of an interactive mobile application to pilot a rapid assay to detect HIV drug resistance mutations in Kenya

JD Vrana, N Panpradist, N Higa, D Ko… - PLOS Global Public …, 2022 - journals.plos.org
Usability is an overlooked aspect of implementing lab-based assays, particularly novel
assays in low-resource-settings. Esoteric instructions can lead to irreproducible test results …

Investigating the compatibility of polymerase chain reaction and oligonucleotide ligation assay for one step detection of point mutations

A Chauhan, B Toley - 2024 - chemrxiv.org
We present a systematic optimization of the components of polymerase chain reaction
(PCR) and oligonucleotide ligation assay (OLA) to combine them into a one-pot reaction …

[PDF][PDF] Implementation of an interactive mobile application to pilot a rapid assay to detect HIV drug resistance mutations in Kenya. PLOS Glob Public Health 2 (2) …

JD Vrana, N Panpradist, N Higa, D Ko, P Ruth… - 2022 - scienceopen.com
Usability is an overlooked aspect of implementing lab-based assays, particularly novel
assays in low-resource-settings. Esoteric instructions can lead to irreproducible test results …