Implementation of white analytical chemistry–assisted analytical quality by design approach to green liquid chromatographic method for concomitant analysis of anti …

P Prajapati, A Shahi, A Acharya… - Journal of …, 2024 - academic.oup.com
According to current concepts of white analytical chemistry (WAC), the use of organic
solvents those are teratogenic and carcinogenic must be avoided for the protection of the …

Chemometric and design of experiments-based analytical quality by design and green chemistry approaches to multipurpose high-pressure liquid chromatographic …

P Prajapati, A Shahi, A Acharya… - Journal of AOAC …, 2023 - academic.oup.com
Background Azilsartan medoxomil (AZL) is an anti-hypertensive drug, and its numerous
FDCs are used for the treatment of hypertension. Numerous chromatographic methods have …

Application of chemometry and design of experiments to green HPTLC method for synchronous estimation of multiple FDCs of cilnidipine

P Prajapati, P Tailor, A Shahi… - Journal of AOAC …, 2022 - academic.oup.com
Background Numerous fixed-dose combinations (FDCs) of cilnidipine (CIL) with
chlorthalidone (CLT) and azilsartan medoxomil (AZL) are used for the treatment of …

Application of Taguchi OA and Box–Behnken design for the implementation of DoE-based AQbD approach to HPTLC method for simultaneous estimation of azilsartan …

P Prajapati, P Tailor, A Shahi… - Journal of …, 2023 - academic.oup.com
Hypertension is the most prominent disease found in people due to stressful routines and
the working environment. The fixed-dose combination (FDC) of azilsartan medoxomil (AZL) …

Robust method operable design region for economical and eco‐friendly chromatographic analysis of azilsartan medoxomil and cilnidipine by incorporating a hybrid …

P Prajapati, A Shahi, A Acharya… - Separation Science …, 2023 - Wiley Online Library
According to the concept of green analytical chemistry, the analytical method development
should be carried out by avoiding or minimizing the usage of toxic organic solvents for the …

[PDF][PDF] Simultaneous estimation of azilsartan and cilnidipine in bulk by RP-HPLC and assessment of its applicability in marketed tablet dosage form

SM ANDHALE, APG NIKALJE - hypertension, 2022 - academia.edu
Objective: This study aims to build up the RP-HPLC process for Azilsartan and Cilnidipine
and authenticate the RP-HPLC process according to ICH validation code Q2R1. Methods …

An investigative review for pharmaceutical analysis of 1, 4-Dihydropyridine-3, 5-Dicarboxylic Acid derivative: Cilnidipine

SR Chaudhari, AA Shirkhedkar - Critical reviews in analytical …, 2021 - Taylor & Francis
Hypertension is commonly a quiet condition, and it expands the risk of heart diseases and
stroke. Calcium delivers a substantial role in cardiovascular functions and hence is essential …

RP-HPLC method for determination of azelnidipine and telmisartan in pharmaceutical dosage form

M Panda, V Dadi, SR Yarraguntla… - Research Journal of …, 2023 - indianjournals.com
An analytical method based on reverse phase-high performance liquid chromatography (RP-
HPLC) has been developed and subsequently validated, which was found to be simple and …

Chemometry and green chemistry-based chromatographic analysis of azilsartan medoxomil, cilnidipine and chlorthalidone in human plasma using analytical quality …

P Prajapati, A Shahi, A Acharya… - Journal of …, 2024 - academic.oup.com
According to the green chemistry approach, the usage of carcinogenic and teratogenic
organic solvents should be minimized in the development of the analytical method for the …

Development and validation of a stability indicating RP-HPLC method for the estimation of chlorthalidone and cilnidipine in combined pharmaceutical dosage form

L Sawaikar, P Kapupara - Research Journal of pharmacy and …, 2020 - indianjournals.com
A simple and a rapid stability indicating RP-HPLC method has been developed for the
estimation of Chlorthalidone and Cilnidipine in their combined dosage form. The separation …