Migraine: disease characterisation, biomarkers, and precision medicine
Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …
Human models of migraine—short-term pain for long-term gain
Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …
From transformation to chronification of migraine: pathophysiological and clinical aspects
Chronic migraine is a neurological disorder characterized by 15 or more headache days per
month of which at least 8 days show typical migraine features. The process that describes …
month of which at least 8 days show typical migraine features. The process that describes …
Chronic migraine: A process of dysmodulation and sensitization
M Su, S Yu - Molecular pain, 2018 - journals.sagepub.com
Chronic migraine is a common chronic daily headache featured by frequent headache
attacks with at least 15 headache days per month, which brings great disease burden to …
attacks with at least 15 headache days per month, which brings great disease burden to …
Pituitary adenylate cyclase-activating polypeptide signalling as a therapeutic target in migraine
Migraine is a disabling neurological disorder that affects more than one billion people
worldwide. The clinical presentation is characterized by recurrent headache attacks, which …
worldwide. The clinical presentation is characterized by recurrent headache attacks, which …
Biomarkers of migraine: an integrated evaluation of preclinical and clinical findings
C Demartini, M Francavilla, AM Zanaboni… - International journal of …, 2023 - mdpi.com
In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …
migraine diagnosis and progression or associated with the response to a specific treatment …
Neuropeptides as a marker for chronic headache
N Riesco, E Cernuda-Morollón, J Pascual - Current Pain and Headache …, 2017 - Springer
Abstract Purpose of Review The purpose of this review is to revise current evidence on
trigemino-vascular system (TVS) neuropeptides as potential biomarkers for chronic primary …
trigemino-vascular system (TVS) neuropeptides as potential biomarkers for chronic primary …
Serum CGRP, VIP, and PACAP usefulness in migraine: a case–control study in chronic migraine patients in real clinical practice
S Pérez-Pereda, M Toriello-Suárez… - Molecular Biology …, 2020 - Springer
Calcitonin gene-related peptide (CGRP), vasoactive intestinal peptide (VIP) and pituitary
adenylate cyclase activating polypetide-38 (PACAP-38) have relevant roles in migraine …
adenylate cyclase activating polypetide-38 (PACAP-38) have relevant roles in migraine …
Emerging drugs for migraine treatment: an update
G Lambru, AP Andreou, M Guglielmetti… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Migraine is a very frequent and disabling neurological disorder. The current
treatment options are old, generally poorly tolerated and not migraine-specific, reflecting the …
treatment options are old, generally poorly tolerated and not migraine-specific, reflecting the …
[HTML][HTML] Targeted orexin and hypothalamic neuropeptides for migraine
LC Strother, A Srikiatkhachorn, W Supronsinchai - Neurotherapeutics, 2018 - Elsevier
The hypothalamus is involved in the regulation of homeostatic mechanisms and migraine-
related trigeminal nociception and as such has been hypothesized to play a central role in …
related trigeminal nociception and as such has been hypothesized to play a central role in …