Challenges and opportunities in carbon capture, utilization and storage: A process systems engineering perspective

MMF Hasan, MS Zantye, MK Kazi - Computers & Chemical Engineering, 2022 - Elsevier
Carbon capture, utilization, and storage (CCUS) is a promising pathway to decarbonize
fossil-based power and industrial sectors and is a bridging technology for a sustainable …

Disaster-resilient design of manufacturing facilities through process integration: principal strategies, perspectives, and research challenges

MM El-Halwagi, D Sengupta… - Frontiers in …, 2020 - frontiersin.org
Extreme events cause significant damage and disruption to the manufacturing sector,
associated supply chains, and adjacent communities. These disastrous shocks may include …

A hierarchical method to integrated solvent and process design of physical CO2 absorption using the SAFT‐γ Mie approach

J Burger, V Papaioannou, S Gopinath… - AIChE …, 2015 - Wiley Online Library
Molecular‐level decisions are increasingly recognized as an integral part of process design.
Finding the optimal process performance requires the integrated optimization of process and …

Optimal solvent design for extractive distillation processes: a multiobjective optimization-based hierarchical framework

T Zhou, Z Song, X Zhang, R Gani… - Industrial & …, 2019 - ACS Publications
Extractive distillation is a widely accepted and commercialized process for separating
azeotropic mixtures compared to conventional distillation. The search for high-performing …

Chemical structure-related drug-like criteria of global approved drugs

F Mao, W Ni, X Xu, H Wang, J Wang, M Ji, J Li - Molecules, 2016 - mdpi.com
The chemical structure of a drug determines its physicochemical properties, further
determines its ADME/Tox properties, and ultimately affects its pharmacological activity …

Integrated solvent and process design exemplified for a Diels–Alder reaction

T Zhou, K McBride, X Zhang, Z Qi… - AIChE Journal, 2015 - Wiley Online Library
A new kind of solvent descriptor obtained from quantum chemical calculations is introduced.
Group contributions to each solvent descriptor are regressed for 71 UNIFAC groups. A …

3-Chloro-3-methyl-2, 6-diarylpiperidin-4-ones as anti-cancer agents: synthesis, biological evaluation, molecular docking, and in silico ADMET prediction

A Ramalingam, N Mustafa, WJ Chng, M Medimagh… - Biomolecules, 2022 - mdpi.com
Piperidine pharmacophore-containing compounds have demonstrated therapeutic efficacy
against a range of diseases and are now being investigated in cancer. A series of 3-chloro-3 …

[PDF][PDF] Computer aided molecular design: fundamentals, methods and applications

AI Papadopoulos11, I Tsivintzelis, P Linke… - Chem., Mol. Sci. and …, 2018 - researchgate.net
Nomenclature dt0015 A Helmholtz free energy dt0020 Ak Matrix of number of occurrences of
molecular groups in molecule k dt0025 ACO Ant colony optimization dt0030 ADI Absorption …

Advanced fuels from ethanol–a superstructure optimization approach

JM Restrepo-Flórez, CT Maravelias - Energy & Environmental Science, 2021 - pubs.rsc.org
We develop a superstructure framework for the design of biorefineries for ethanol upgrading
into advanced biofuels to replace gasoline, jet fuel or diesel. The framework integrates …

Optimization‐based framework for computer‐aided molecular design

AP Samudra, NV Sahinidis - AIChE Journal, 2013 - Wiley Online Library
A new framework to automate, augment, and accelerate steps in computer‐aided molecular
design is presented. The problem is tackled in three stages:(1) composition design,(2) …