By controlling nutrient cycling and biomass production at the base of the food web,
interactions between phytoplankton and bacteria represent a fundamental ecological …

Bacteria are an exceedingly diverse group of organisms whose molecular exploration is
experiencing a renaissance. While the classical view of bacterial gene expression was …

Bacteria colonize almost all parts of the human body and can differ significantly. However,
the population level transcriptomics measurements can only describe the average bacteria …

INTRODUCTION Bacteria heterogeneously activate gene expression programs in response
to environmental changes, stress, and other stimuli. Such behavior may serve as a bet …

Bacteria respond to changes in their environment with specific transcriptional programmes,
but even within genetically identical populations these programmes are not homogenously …

Despite longstanding appreciation of gene expression heterogeneity in isogenic bacterial
populations, affordable and scalable technologies for studying single bacterial cells have …

Background Alzheimer's disease (AD) is the most common form of dementia. This
neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting …

Accurate measurements of promoter activities are crucial for predictably building genetic
systems. Here we report a method to simultaneously count plasmid DNA, RNA transcripts …

Highlights•Single cell Raman spectra (SCRS) are label-free and intrinsic biochemical
profiles of single microbial cells.•A number of bands of SCRS shift if cells are labeled with …

Single-cell RNA sequencing (scRNA-Seq) is transforming our ability to characterize cells,
particularly rare cells that are often overlooked in bulk population analytical approaches …