To serve vision, vertebrate rod and cone photoreceptors must detect photons, convert the
light stimuli into cellular signals, and then convey the encoded information to downstream …

Vertebrate photoreceptor cells are exquisite light detectors operating under very dim and
bright illumination. The photoexcitation and adaptation machinery in photoreceptor cells …

The G protein-coupled receptor (GPCR) rhodopsin self-assembles into supramolecular
structures in native bilayers, but the structural determinants of receptor oligomerization are …

We introduce the software package ReaDDy for simulation of detailed spatiotemporal
mechanisms of dynamical processes in the cell, based on reaction-diffusion dynamics with …

The visual pigment rhodopsin belongs to the family of G protein-coupled receptors that can
form higher oligomers. It is controversial whether rhodopsin forms oligomers and whether …

Particle-based reaction-diffusion algorithms facilitate the modeling of the diffusional motion
of individual molecules and the reactions between them in cellular environments. A …

Rhodopsin is a prototypical G protein-coupled receptor (GPCR)–a member of the
superfamily that shares a similar structural architecture consisting of seven-transmembrane …

Any aspect of cell activity is regulated by extracellular signals that are recognized, decoded,
and transduced inside the cell via different classes of plasma membrane receptors. 1À3 G …

Rhodopsins are densely packed in rod outer-segment membranes to maximize photon
absorption, but this arrangement interferes with transducin activation by restricting the …

Rhodopsin is the light receptor in photoreceptor cells of the retina and a prototypical G
protein-coupled receptor. Two types of quaternary structures can be adopted by rhodopsin. If …