Applications of the conceptual density functional theory indices to organic chemistry reactivity

LR Domingo, M Ríos-Gutiérrez, P Pérez - Molecules, 2016 - mdpi.com
Theoretical reactivity indices based on the conceptual Density Functional Theory (DFT) have
become a powerful tool for the semiquantitative study of organic reactivity. A large number of …

Conceptual density functional theory

P Geerlings, F De Proft, W Langenaeker - Chemical reviews, 2003 - ACS Publications
Chemists prefer to describe reactions in terms of the properties of isolated systems, chosen
to yield information on the behavior of a given reactant under perturbation by another …

Understanding the local reactivity in polar organic reactions through electrophilic and nucleophilic Parr functions

LR Domingo, P Pérez, JA Sáez - RSC advances, 2013 - pubs.rsc.org
Building upon our recent studies devoted to the bonding changes in polar reactions [RSC
Advances, 2012, 2, 1334 and Org. Biomol. Chem., 2012, 10, 3841], we propose herein two …

Update 1 of: electrophilicity index

PK Chattaraj, DR Roy - Chemical reviews, 2007 - ACS Publications
Chemistry is the science of bond making and bond breaking. A thorough knowledge of these
processes in the course of the chemical reaction lies at the heart of any reaction mechanism …

The nucleophilicity N index in organic chemistry

LR Domingo, P Pérez - Organic & biomolecular chemistry, 2011 - pubs.rsc.org
The nucleophilicity N index (J. Org. Chem. 2008, 73, 4615), the inverse of the
electrophilicity,, and the recently proposed inverse of the electrodonating power,,(J. Org …

Understanding the mechanism of polar Diels–Alder reactions

LR Domingo, JA Sáez - Organic & biomolecular chemistry, 2009 - pubs.rsc.org
A good correlation between the activation energy and the polar character of Diels–Alder
reactions measured as the charge transfer at the transition state structure has been found …

Electrophilicity index revisited

R Pal, PK Chattaraj - Journal of Computational Chemistry, 2023 - Wiley Online Library
This review aims to be a comprehensive, authoritative, critical, and accessible review of
general interest to the chemistry community; because the electrophilicity index is a very …

A further exploration of a nucleophilicity index based on the gas-phase ionization potentials

P Jaramillo, LR Domingo, E Chamorro… - Journal of Molecular …, 2008 - Elsevier
An empirical nucleophilicity index based on the gas-phase ionization potentials has been
recently shown to be useful categorizing and settling the nucleophilicity power of a series of …

[HTML][HTML] Comparison of the binding energies of approved mpox drugs and phytochemicals through molecular docking, molecular dynamics simulation, and ADMET …

RK Mohapatra, A Mahal, A Ansari, M Kumar… - Journal of Biosafety and …, 2023 - Elsevier
The mpox (previously monkeypox) outbreak in more than 100 non-endemic countries in
2022 posed a serious global health concern. Mpox is emerging as a global public health …

Synthesis, spectroscopic (13C/1H-NMR, FT-IR) investigations, quantum chemical modelling (FMO, MEP, NBO analysis), and antioxidant activity of the bis …

A Ouaket, A Chraka, I Raissouni, MA El Amrani… - Journal of Molecular …, 2022 - Elsevier
In the current study, we first synthesized the molecule 1, 2-Bis (2-benzimidazolyl)-1, 2-
ethanediol, called C1. The structural properties of C1 were explored by spectroscopic …