Environmental chemical exposures and mitochondrial dysfunction: a review of recent literature

A Reddam, S McLarnan, A Kupsco - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review Mitochondria play various roles that are important for cell
function and survival; therefore, significant mitochondrial dysfunction may have chronic …

Polysaccharide-based nanomedicines targeting lung cancer

AA Bhat, G Gupta, KS Alharbi, O Afzal, ASA Altamimi… - Pharmaceutics, 2022 - mdpi.com
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …

PCR based determination of mitochondrial DNA copy number in multiple species

JP Rooney, IT Ryde, LH Sanders, EH Howlett… - … : Methods and Protocols, 2015 - Springer
Mitochondrial DNA (mtDNA) copy number is a critical component of overall mitochondrial
health. In this chapter, we describe methods for isolation of both mtDNA and nuclear DNA …

Particulate matter toxicity is Nrf2 and mitochondria dependent: the roles of metals and polycyclic aromatic hydrocarbons

M Pardo, X Qiu, R Zimmermann… - Chemical research in …, 2020 - ACS Publications
Particulate matter (PM), an important component of air pollution, induces significant adverse
health effects. Many of the observed health effects caused by inhaled PM are associated …

Mitochondria, energetics, epigenetics, and cellular responses to stress

DT Shaughnessy, K McAllister, L Worth… - Environmental …, 2014 - ehp.niehs.nih.gov
Background: Cells respond to environmental stressors through several key pathways,
including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA …

Effect of Ambient PM2.5 on Lung Mitochondrial Damage and Fusion/Fission Gene Expression in Rats

R Li, X Kou, H Geng, J **e, Z Yang… - Chemical research in …, 2015 - ACS Publications
Exposure to ambient fine particulate matter (PM2. 5) increases the risk of respiratory
disease. Although previous mitochondrial research has provided new information about PM …

A state-of-the-science review of using mitochondrial DNA copy number as a biomarker for environmental exposure

Q Cheng, QQ Liu, CA Lu - Environmental Pollution, 2024 - Elsevier
Mitochondria are bioenergetic, biosynthetic, and signaling organelles in eukaryotes, and
contain their own genomes, mitochondrial DNA (mtDNA), to supply energy to cells by …

Mitochondria and mitochondrial DNA as relevant targets for environmental contaminants

DA Roubicek, NC de Souza-Pinto - Toxicology, 2017 - Elsevier
The mitochondrial DNA (mtDNA) is a closed circular molecule that encodes, in humans, 13
polypeptides components of the oxidative phosphorylation complexes. Integrity of the …

An overview of studies on the hazards, component analysis and suppression of fumes in asphalt and asphalt mixtures

M Wang, P Li, T Nian, Y Mao - Construction and Building Materials, 2021 - Elsevier
As the main building materials for highway construction, asphalt and asphalt mixture will
release large quantities of highly hazardous fume at high temperatures. Due to possible …

The mitochondrial DNA content of cumulus granulosa cells is linked to embryo quality

V Desquiret-Dumas, A Clément, V Seegers… - Human …, 2017 - academic.oup.com
STUDY QUESTION Could the mitochondrial DNA (mtDNA) content of cumulus granulosa
cells (CGCs) be related to oocyte competence? SUMMARY ANSWER The quality of …