Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

Nonactivated aziridine with an electron-donating group at the ring nitrogen should be
activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen …

The selective introduction of fluorine onto the skeleton of an aminocyclopentane or
cyclohexane carboxylate has been developed through a novel and efficient fluoride opening …

Nucleophilic fluorination is one of the fundamental reactions in organic chemistry, as well as
a convenient tool for the synthesis of fluorinated building blocks with a potential biological …

The first asymmetric nucleophilic fluorination at the sp3-tertiary carbon center has been
developed using inexpensive tetrabutylammonium fluoride (TBAF) without any …

Herein we report a novel methodology for the asymmetric synthesis of 3-substituted
piperidines from readily available chiral building blocks. This method, which features a novel …

Australine (1), 7-epi-australine (2), and their C-7-fluorinated derivatives 4 and 5 have been
synthesized efficiently from d-arabinose-derived cyclic nitrone 11. Fluorination at the C-7 …

A convenient approach toward nonactivated 1-alkyl-2-(trifluoromethyl) azetidines as a new
class of constrained azaheterocycles was developed starting from ethyl 4, 4, 4 …

Chiral aziridine‐2‐carboxylates have two important functional groups, the carboxylate group
and aziridine ring, that are useful for synthetic purposes. As both (2R)‐and (2S)‐aziridine‐2 …

The asymmetric synthesis of α‐heterofunctionalized α‐and β‐amino acid derivatives has
been a heavily investigated topic over the last years, benefiting from the development of …