Mitochondrial signal transduction

M Picard, OS Shirihai - Cell metabolism, 2022 - cell.com
The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic,
maternally inherited, energy-transforming, biosynthetic, and signaling organelles that …

Reactive oxygen species signalling in plant stress responses

R Mittler, SI Zandalinas, Y Fichman… - … reviews Molecular cell …, 2022 - nature.com
Reactive oxygen species (ROS) are key signalling molecules that enable cells to rapidly
respond to different stimuli. In plants, ROS play a crucial role in abiotic and biotic stress …

Calcium signaling and reactive oxygen species in mitochondria

E Bertero, C Maack - Circulation research, 2018 - ahajournals.org
In heart failure, alterations of Na+ and Ca2+ handling, energetic deficit, and oxidative stress
in cardiac myocytes are important pathophysiological hallmarks. Mitochondria are central to …

Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release

DB Zorov, M Juhaszova, SJ Sollott - Physiological reviews, 2014 - journals.physiology.org
Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …

[HTML][HTML] Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: a mechanism involving calcium overload/XO/ROS/mPTP pathway

P Zhu, S Hu, Q **, D Li, F Tian, S Toan, Y Li, H Zhou… - Redox biology, 2018 - Elsevier
Abstract Receptor-interacting protein 3 (Ripk3)-mediated necroptosis contributes to cardiac
ischaemia-reperfusion (IR) injury through poorly defined mechanisms. Our results …

The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology

DB Graves - Journal of Physics D: Applied Physics, 2012 - iopscience.iop.org
Reactive oxygen species (ROS) and the closely related reactive nitrogen species (RNS) are
often generated in applications of atmospheric pressure plasmas intended for biomedical …

ROS signaling: the new wave?

R Mittler, S Vanderauwera, N Suzuki, GAD Miller… - Trends in plant …, 2011 - cell.com
Reactive oxygen species (ROS) play a multitude of signaling roles in different organisms
from bacteria to mammalian cells. They were initially thought to be toxic byproducts of …

ROS-induced ROS release in plant and animal cells

SI Zandalinas, R Mittler - Free Radical Biology and Medicine, 2018 - Elsevier
Reactive oxygen species (ROS) play a key signaling role in plant and animal cells. Among
the many cellular mechanisms used to generate and transduce ROS signals, ROS-induced …

Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain

S Chenna, WJH Koopman… - … of Physiology-Cell …, 2022 - journals.physiology.org
Reactive oxygen species (ROS) are recognized both as damaging molecules and
intracellular signaling entities. In addition to its role in ATP generation, the mitochondrial …

The inflammasome: an integrated view

O Gross, CJ Thomas, G Guarda… - Immunological …, 2011 - Wiley Online Library
An inflammasome is a multiprotein complex that serves as a platform for caspase‐1
activation and caspase‐1‐dependent proteolytic maturation and secretion of interleukin‐1β …